Table 1: Oxidative stress biomarkers in patients with vaginitis.
Samples |
Results |
References |
100 female patients with nonspecific vaginitis |
↑mucosa epithelial cell apoptosis; ↑MDA; ↑H2O2; ↑DNA damage of mucosa epithelial cells; ↑caspase 3 expression; ↓Bcl2; ↑Bax; ↑cytochrome C in mucosa epithelial cells; ↓CAT activity; ↑SOD |
[47] |
|
|
|
257 patients with vaginitis |
↑MDA; ↑H2O2; ↓CAT activity; ↓vitamin C levels |
[8] |
|
|
|
35 women with bacterial vaginosis |
↑Number of epithelial cells; ↑caspase-3; ↑apoptosis; p-↑IκBα; ↑c-Fos |
[48] |
|
|
|
45 women with vaginitis |
↑Serum disulphide level; ↑serum disulphide/native thiol ratio; ↓native /total thiol; ↑oxidative stress; ↑inflammation |
[49] |
24 women with vulvovaginal candidiasis and cytolytic vaginosis
|
↑Oxidative stress; ↑inflammation; ↑apoptosis |
[50] |
Co-cultured human monocyte-derived macrophages with T. Vaginalis
|
↑TNF-α, ↑IL-1β, ↑IL-6; ↑nitric oxide; ↑iNOS |
[51] |
Incubation of human neutrophils with T. Vaginalis
|
↑ROS; ↑caspase-3 activation; ↑apoptosis |
[52] |
Plasma and tissue samples of diabetic rats |
↓MDA; ↓glutathione; ↓ascorbic acid |
[53] |