Table 1: Summary of medical therapy main features.
| Medical therapy | ||
| Indications | Short-term control of symptoms in symptomatic women. | |
| Suitable patients | Women in perimenopausal age, women scheduled for surgery, patients not suitable for surgery because of contextual medical reasons. | |
| GnRHa | SPRMs | |
| Advantages | Good symptom relief for limited periods. | Absence of estrogen deficiency effect; long-lasting effect/Prolonged therapy without menopausal symptoms. |
| Adverse events |
- Transient/Rebound Effect. - Menopausal Symptoms, Bone Loss. |
Mifepristone: - Endometrial Hyperplasia. |
GnRHa: Gonadotropin Releasing Hormone analog; SPRM: Selective Progesterone Receptor Modulator.