Table 2: Key studies on parental consanguinity and ovarian reserve in PCOS.
|
Study (Author, Year) |
Journal |
Region |
Study Design |
Sample Size |
Key Findings (AMH, AFC, FSH) |
Association with Ovarian Reserve |
Noted Limitations |
|
Melado, et al. 2022 [51] |
Reproductive BioMedicine Online |
Arabian Peninsula |
Retrospective observational |
2198 |
Significantly lower AMH (p = 0.036) and AFC (p = 0.003) in consanguineous group after age adjustment |
Associated with reduced ovarian reserve |
Women in consanguineou s group were significantly younger, but adjusted analysis controlled for this. |
|
Mohamed M, et al. 2024 [53] |
Research Gat e, PMC |
Oman |
Retrospective cohort |
414 |
No statistically significant difference in AMH, AFC, and FSH between groups |
Does not affect ovarian reserve |
AMH not tested in all participants due to financial constraints. |