Table 2: Key studies on parental consanguinity and ovarian reserve in PCOS.

 

Study (Author, Year)

 

 

 

Journal

 

 

 

Region

 

 

 

Study Design

 

 

Sample Size

 

Key Findings (AMH, AFC, FSH)

Association with Ovarian Reserve

 

 

Noted Limitations

 

 

 

 

 

 

Melado, et al. 2022 [51]

 

 

 

 

 

 

Reproductive BioMedicine Online

 

 

 

 

 

 

 

Arabian Peninsula

 

 

 

 

 

 

 

Retrospective observational

 

 

 

 

 

 

 

 

2198

 

Significantly lower AMH (p = 0.036) and AFC (p = 0.003)

in consanguineous group after age adjustment

 

 

 

 

Associated with reduced ovarian reserve

Women in consanguineou s group were significantly younger, but adjusted analysis controlled for this.

 

 

 

Mohamed M, et al. 2024 [53]

 

 

 

 

Research Gat e, PMC

 

 

 

 

 

Oman

 

 

 

 

Retrospective cohort

 

 

 

 

 

414

No statistically significant difference in AMH, AFC,

and FSH between groups

 

 

Does not affect ovarian reserve

AMH not tested in all participants due to financial constraints.