Table 1: Clinicopathological features of reported cases of cranial intraosseous angiolipoma.

Reference

Age (years)/Gender

Location

Period of Expansion

History of Head Trauma

Clinical Features/Neurological Examination

Radiographic Findings

Histopathology*

 

Amir jamshidi, et al. [10]

 

41/Female

 

Right frontotemporo-parietooccipital

 

2 years

 

No

 

Tender to palpation, Headache

 

X-ray, CT, & MRI: 20 cm expansile, Non-enhancing lesion extending along the diploe and destroying the internal and external tables with cerebral compression

 

-Gross: Yellow lipomatous bone with cancellous and vascular components;
-Histo: Some lesional vessels with fibrin thrombi, no cellular a typia or mitotic figures;
-IHC: S100 neg, CD34 pos, Sudan black pos

 

Atilgan, et al. [7]

 

16/Female

 

Right frontal

 

"long time"

 

No

 

Swelling, Headache

 

CT: 2 cm well defined lesion with no bone destruction or soft tissue component

 

-Gross: Yellow-brown solid lesion;
-Histo: Some lesional vessels with neutrophils and fibrin thrombi, no mitosis or necrosis, Average of 10 mast cells per 1 HPF;
-IHC: CD34 pos, CD31 pos, VEGF pos, TGFbetapos, TNFalphapos

 

Nguyen, et al. [8]

 

55/Male

 

Right frontal

 

-

 

-

 

Headache, Nausea, Vomiting, Diplopia, Facial asymmetry [concurrently diagnosed with metastatic invasive ductal breast carcinoma]

 

CT & MRI: 4.3 cm heterogeneously enhancing lesion with cerebral compression, But without involvement of overlying soft tissue

 

-Gross: Well circumscribed, mixed areas of firm-to-soft tan and red lobulated tissue;
-Histo: No cytologic atypia or mitoses;
-IHC: Pankeratinneg

 

Singh, et al. [6]

 

30/Female

 

Right parietal

 

5 years, following pregnancy

 

No

 

Altered sensation over area without pain on palpation

 

CT & MRI: 6.4 cm mass with expansion of diploid space and cerebral compression

 

-Histo: No cytologic atypia;
-IHC: epithelial membrane antigen neg

 

Yu, et al. [9]

 

50/Male

 

Right parietal

 

11 years

 

Minor trauma

 

Swelling

 

CT: 7 cm spiculated, Non-enhancing lesion with cerebral compression

 

-Gross: Yellow-brown lesion of variable consistency;
-Histo: Well circumscribed non encapsulated lesion, scattered mast cells, no thrombi

 

Our case

 

61/Female

 

Left frontoparietal

 

6 months

 

Minor trauma

 

Swelling

 

Bone scan, CT & MRI: 4.4 cm expansile, Spiculated, Enhancing lesion with superficial soft tissue component and cerebral compression

 

-Gross: Dark red-grey cut surface;
-Histo: No cytologic atypia or mitosis or necrosis;
-IHC: CD34 pos, S100 pos

 

*All specimens histologically demonstrated an admixture of mature adipose tissue and thin-walled blood vessels. (Histo: Histology; IHC: Immunohistochemistry; Neg: Negative; Pos: Positive; HPF: High power field).