Summary of research studies investigating risk factors for post-adenotonsillectomy respiratory adverse events in paediatric OSA patients.

Table 5: Summary of research studies investigating risk factors for post-adenotonsillectomy respiratory adverse events in paediatric OSA patients.

Authors	Statistically significant risk factorsa
Kieran, et al. [13]	Univariate analysis: Age < 2 Age < 3 Weight < 20 kg Weight < 15 kg OSA Tonsillitis Multivariate analysis: Weight < 20 kg OSA (clinical diagnosis) Neurologic disease Cardiac disease Pulmonary disease Trisomy 21 Other syndrome
Statham, et al. [14]	Age < 3 Age < 2
Brown, et al. [10]	Associated medical condition SaO₂ nadir < 80%
Wilson, et al. [16]	SaO₂ nadir ≤ 80% OAH ≥ 5/hr
Biavati, et al. [17]	1) Associated medical condition: a) Cerebral palsy b) Seizures c) Congenital heart disease 2) Age ≤ 3 3) Prematurity
Rosen, et al. [19]	1) Age (< 2) 2) Associated medical problems (eg craniofacial abnormalities, hypotonia, morbid obesity) 3) Polysomnogram RDI (> 40) 4) Polysomnogram O₂ saturation nadir (< 70%) 5) UPPP performed with T&A
McColley, et al. [20]	Univariate Analysis: 1) Age < 3 2) Obstructive Event Index > 10/hr 3) Failure to thrive 4) Cardiac abnormality 5) Craniofacial abnormality 6) Chest film abnormality Multivariate logistic regression 1) Age < 3 2) OEI > 10/h

^a: p-value ≤ 0.05, OEI = Obstructive Event Index; RDI = Respiratory Disturbance Index; UPPP = Uvulopalatopharyngoplasty; T&A = Tonsillectomy and Adenoidectomy; SaO₂ = Arterial Saturation of Oxygen; OAH index = Obstructive Apnoea-Hypopnea index.