Characteristics of individuals diagnosed with both narcolepsy and PCOS.

Table 1: Characteristics of individuals diagnosed with both narcolepsy and PCOS.

	Age (yrs)	BMI kg/m²	EDS (ESS)	Cataplex y	HH	Sleep paralysis	PSG/MSLT	HLA testing	CSF hypocretin level	Other medical problems	PCOS presentation and biochemical screening
Presented Case	16	32.6	+ (17)	+	-	+	PSG: SL = 3 mins; REM Latency = 57 MSLT: SL = 4.5; 2 SOREMs		Not done	PCOS, high HbA1C, overweight, stomach problems and hypothyroidism	Irregular menses, increased facial, hands and back hair, elevated testosterone 92 ng/dl decreased 17-hydroxypregnenolone 29 elevated insulin levels 34.7 IU/ml
Peraita-Adrados R, et al. [8]	10	23.5	+	+	-	-	PSG - no OSA MSLT: SL = 1 min; 4 SOREM_s	+ HLA DQB1*0602	Undetectable (< 40)	PCOS. arachnoid cyst, empty sella, congenital hip dislocation, MDD, precautious puberty, academic problems	Amenorrhea with previous signs of precocious puberty, hyperandrogenism and hyperinsulinaemia. ultrasound showing polycystic ovaries
Konermann M, et al. [9]	25	40.9	+(19)	unknown	unknown	unknown	PSG: SL = 3 mins; REM Latency = 5 min MSLT: SL = 0-2 min; 4 SOREMs	+ HLA-DR 15	Not done	PCOS, Mild OSA (AHI = 15.4)	Oligomenorrhea, infertility indicating oligo or an-ovulation, obesity, hirsutism, elevated testosterone 134.2 ng/dl, increased insulin of 489 m U/L and C-peptide protein > 14
Yau MM, et al. [10]	14		+ (Not done)	+	+	+	PSG: Normal MSLT: SL = 11.2 min; No SOREMs with modafinil	Not done	Not done	PCOS, obesity, insulin resistance	obesity, insulin resistance

BMI: Body Mass Index; EDS: Excessive Daytime Sleepiness; HH: Hypnagogic and Hypnopompic Hallucination; PSG: Polysomnography; MSLT: Mean Sleep Latency Test; HLA: Human Leucocyte Antigen; PCOS: Polycystic Ovarian Disease; Hb: Hemoglobin; MDD: Major Depressive Disorder; SL: Sleep Latency; SL MSLT: Sleep Latency in Mean Sleep Latency Test Naps; OSA: Obstructive Sleep Apnea.