Table 4: Weighted agreement kappa coefficient between different disease activity scores as assessed by the DAS28-CRP, DAS28-CRP-3, Tamhane, et al. DAS28-CRP, and current study-specific DAS28-CRP according to the conventional threshold (DAS28-ESR ≤ 5.1) and Castrejon threshold (DAS28-CRP ≤ 4.9) for moderate disease activity
| DAS28-ESR conventional threshold | DAS28-CRP Castrojen threshold | ||||||
| Moderate (≤ 5.1) | High (> 5.1) | Kappa, (95% CI) | Moderate (≤ 4.9) | High (> 4.9) | Kappa, (95% CI) | ||
| DAS28-CRP | 0.393 (0.180, 0.607) | ||||||
| Moderate (≤ 4.999) | 12 (16.2) | 15 (20.2) | |||||
| High (> 4.999) | 4 (5.4) | 43 (58.1) | |||||
| DAS28-CRP-3 | 0.463 (0.234, 0.692) | 0.759 (0.603, 0.915) | |||||
| Moderate (≤ 4.494) | 11 (14.9) | 10 (13.5) | Moderate (≤ 4.708) | 21 (28.4) | 6 (8.1) | ||
| High (> 4. 494) | 5 (6.8) | 48 (64.9) | High (> 4. 708) | 2 (2.7) | 45 (60.8) | ||
| Tamhane, et al. DAS28-CRP | 0.375 (0.176, 0.574) | 0.871 (0.745, 0.994) | |||||
| Moderate (≤ 5.697) | 13 (17.6) | 18 (24.3) | Moderate (≤ 5.488) | 20 (27.0) | 1 (1.4) | ||
| High (> 5.697) | 3 (4.1) | 40 (54.1) | High (> 5.488) | 3 (4.1) | 50 (67.6) | ||
| Current study data-specific DAS28-CRP | 0.553 (0.342, 0.763) | 0.726 (0.559, 0.892) | |||||
| Moderate (≤ 5.553) | 13 (17.6) | 10 (13.5) | Moderate (≤ 5.593) | 20 (27.0) | 6 (8.1) | ||
| High (> 5.553) | 3 (4.1) | 48 (64.9) | High (> 5.593) | 3 (4.1) | 45 (60.8) | ||