Table
3: Pregnancy outcomes in 129 women with systemic
sclerosis after the disease onset according to ATA positivity.
|
Events
after disease onset |
No. of events: total
No. of Topo+ (%) |
No. of events: total No. of Topo - (%) |
OR
(95% CI) |
P-value |
|
Pregnancies |
|
|
|
|
|
Gravid
women |
22:66
(33.3) |
9:30
(30.0) |
1.22
(0.76 - 4.65) |
P = 0.67 |
|
Gravidity
|
34:76
(44.7) |
10:31
(32.0) |
1.70
(0.48 - 3.11) |
P =
0.24 |
|
Pregnancy
outcomes |
|
|
|
|
|
Women
with abortion |
5:66
(7.50) |
3:30
(10.0) |
0.73
(0.164 - 3.31) |
P =
0.69 |
|
No.
of abortions |
11:72
(16.4) |
3:30
(10.0) |
1.62
(0.42 - 6.29) |
P =
0.48 |
|
Women
with RPL |
3:66
(4.55) |
0:30 |
3.31
(0.16 - 66.1) |
P =
0.43 |
|
No.
of RPL |
9:72
(12.5) |
0:30 |
8.98
(0.50 - 159.4) |
P =
0.13 |
|
No.
of spontaneous abortions |
11:72
(15.0) |
2:30
(6.70) |
2.02
(0.42 - 9.71) |
P =
0.37 |
|
No.
of therapeutic abortions |
0:66 |
1:30 |
0.15
(0.01 - 3.74) |
P =
0.24 |
|
Women
with delivery |
20:66 |
6:30 |
1.74
(0.62 - 4.90) |
P =
0.29 |
|
No.
of deliveries |
23:69 |
7:31 |
|
|
|
Twin
pregnancy |
0 |
0 |
NOT
APPLICABLE |
- |
|
Women
with term delivery |
15:66
(22.7) |
6:30
(20.0) |
1.17
(0.41 - 3.41) |
P =
0.76 |
|
No.
of term deliveries |
18:69
(23.1) |
7:31
(22.5) |
1.21
(0.45 - 3.30) |
P =
0.70 |
|
Women
with preterm delivery |
5:66
(7.5) |
0:30 |
5.45
(0.29 - 101.90) |
P =
0.25 |
|
No.
of preterm deliveries |
5:66
(7.5) |
0:30 |
5.45
(0.29 - 101.90) |
P =
0.25 |
|
Women
with stillbirth |
1:66
(1.5) |
0:30 |
1.39
(0.05 - 35.29) |
P =
0.83 |
|
Number
of stillbirths |
2:66
(3.0) |
0:30 |
2.36
(0.11 - 50.77) |
P =
0.58 |
|
Women
with unsuccessful pregnancy |
3:66
(4.5) |
2:30
(6.6) |
0.66
(0.10 - 4.21) |
P =
0.66 |
|
Delivery
mode |
|
|
|
|
|
Number
of NVD |
10:68
(14.7) |
4:31
(12.9) |
1.16
(0.33 - 4.05) |
P =
0.81 |
|
Number
of caesarian sections |
13:60
(21.6) |
3:30
(10) |
2.20
(0.57 - 8.41) |
P =
0.24 |
|
Obstetric
complications |
|
|
|
|
|
Gestational
hypertension |
0 |
0 |
NOT
APPLICABLE |
- |
|
Women
with preeclampsia |
0 |
0 |
NOT
APPLICABLE |
- |
|
No.
of preeclampsia |
0 |
0 |
NOT
APPLICABLE |
- |
|
Newborn
outcomes |
|
|
|
|
|
Women
with very low birth weight infants (< 1500 g) |
2:66
(3.0) |
0:30 |
2.36
(0.11 - 50.77) |
|
|
No.
of neonatal deaths |
0 |
0 |
NOT
APPLICABLE |
|
#
No. (%): Number (percentage); *TOPO+:
Anti-Topoisomerase 1 positivity; **TOPO-: Anti-Topoisomerase 1
Negativity; £OR (CI95%): Odds Ratio (confidence interval); ŧ
NA: Not Applicable.