Table 1: Socio demographic, laboratory parameters, and disease activity of studied groups (n = 90).
Active LN N = 30 |
Inactive LN N = 30 |
Controls N = 30 |
p-value | |
Socio demographic Age Mean (SD) years |
32.90 (12.23) |
38.27 (12.19) |
35.60 (12.72) |
0.250 |
Gender Male (n, %) Female (n, %) |
0 (0) 30 (100) |
2 (6.67) 28 (93.33) |
11 (36.67) 19 (63.33) |
< 0.001 |
Marital Status Married (n, %) Unmarried (n, %) |
21 (70) 9 (30) | 22 (73.33) 8 (26.67) | 16 (53.33) 14 (46.67) | 0.223 |
Race Malay (n, %) Chinese (n, %) |
29 (96.67) 1 (3.33) |
25 (83.33) 5 (16.67) |
29 (96.67) 1 (3.33) |
0.085 |
Disease Duration Months |
80.97 (71.64) |
98.03 (91.11) |
- |
< 0.001 |
Occupation Employed (n, %) Unemployed (n, %) |
16 (53.33) 14 (46.67) |
23 (76.67) 7 (23.33) |
14 (46.67) 16 (53.33) |
0.061 |
Laboratory parameters Serum C3 Mean (SD) (g/l) Serum C4 Mean (SD) (g/l) Anti-dsDNA Positive: 1:10-1:160, n(%) Negative: < 1:10, n(%) Uprot/Ucreat Mean (SD)Disease activity SLEDAI Mean (SD) |
0.80 (0.38) 0.16 (0.09) 18 (60.0) 12 (40.0) 2.32 (4.95) 10.20 (5.53) |
0.99 (0.25) 0.23 (0.11) 8 (26.7) 22 (73.3) 0.20 (0.32) 2.57 (2.54) |
1.09 (0.20) 0.25 (0.07) - 0.05 (0.03) - |
0.001 0.001 0.009 0.004 < 0.001 |
rSLEDAI Mean (SD) |
6.93 (3.14) |
- |
- |
< 0.001 |
Abbreviations: LN = Lupus Nephritis; C3 = Complement 3; C4 = Complement 4; anti-dsDNA = Anti-double stranded DNA; Uprot/Ucreat = Urine Protein/urine Creatinine; SLEDAI = Systemic Lupus Erythematosus Disease Activity Index; rSLEDAI = Renal Systemic Lupus Erythematosus Disease Activity Index. p < 0.05 is significant.