Table 1: Socio demographic, laboratory parameters, and disease activity of studied groups (n = 90).




Active LN

N = 30

Inactive LN

N = 30

Controls

N = 30

p-value

Socio demographic

Age

Mean (SD) years



32.90 (12.23)



38.27 (12.19)



35.60 (12.72)



0.250

Gender

Male (n, %)

Female (n, %)


0 (0)

30 (100)


2 (6.67)

28 (93.33)


11 (36.67)

19 (63.33)


< 0.001


Marital Status

Married (n, %)

Unmarried (n, %)


21 (70)

9 (30)


22 (73.33)

8 (26.67)


16 (53.33)

14 (46.67)


0.223


Race

Malay (n, %)

Chinese (n, %)


29 (96.67)

1 (3.33)


25 (83.33)

5 (16.67)


29 (96.67)

1 (3.33)


0.085

Disease Duration

Months


80.97 (71.64)


98.03 (91.11)


-


< 0.001

Occupation

Employed (n, %)

Unemployed (n, %)


16 (53.33)

14 (46.67)


23 (76.67)

7 (23.33)


14 (46.67)

16 (53.33)


0.061


Laboratory parameters

Serum C3

Mean (SD) (g/l)

Serum C4

Mean (SD) (g/l)

Anti-dsDNA

Positive: 1:10-1:160, n(%)

Negative: < 1:10, n(%)

Uprot/Ucreat

Mean (SD)

Disease activity

SLEDAI

Mean (SD)



0.80 (0.38)


0.16 (0.09)


18 (60.0)

12 (40.0)


2.32 (4.95)



10.20 (5.53)



0.99 (0.25)


0.23 (0.11)


8 (26.7)

22 (73.3)


0.20 (0.32)



2.57 (2.54)



1.09 (0.20)


0.25 (0.07)


-



0.05 (0.03)



-



0.001


0.001


0.009



0.004



< 0.001

rSLEDAI

Mean (SD)


6.93 (3.14)


-


-


< 0.001

Abbreviations: LN = Lupus Nephritis; C3 = Complement 3; C4 = Complement 4; anti-dsDNA = Anti-double stranded DNA; Uprot/Ucreat = Urine Protein/urine Creatinine; SLEDAI = Systemic Lupus Erythematosus Disease Activity Index; rSLEDAI = Renal Systemic Lupus Erythematosus Disease Activity Index. p < 0.05 is significant.