Table 5: Comparison between 38 patients with miocardial infarct (MI) and 279 patients without CV events; 14 patients with heart failure and 279 patients without CV events.

MI (n. 38) Without CV events (n. 279) p Heart failure (n. 14) p
Demographics F/M 8/15 224/75 0.0001 11/3 1.0
Mean age at onset, years (SD) 55 (11) 45.7 (15.6) 0.0009a 54.5 (13.4) 0.04a
Mean age at baseline, years (SD) 60 (9.9) 54.3 (11.9) 0.01a 63.3 (9.6) 0.006a
Mean drug exposure duration, years (SD) 11.3 (7.3) 18.4 (8.8) 0.2a 11.3 (7.3) 0.48a
Mean RA duration at last observation, years (SD) 13.28 (7.4) 18.4 (8.8) 0.6a 19.4 (7.1) 0.7a
Anti-TNF alfa exposure, n. (%) 8/38 (21) 65/214 (30.3) 0.33 8/14 (57) 0.038
Comorbidities Arterial hypertension (%) 7/32 (21.8) 41/156 (26.2) 0.66 5/11 (45.5) 0.17
Smoking habits (%) 4/13 (30.7) 37/156 (23.7) 0.5 1/11 (9) 0.46
Dyslipidaemia (%) 13/32 (40.6) 17/153 (11.1) < 0.0001 5/14 (35.7) 0.038
Familiar CV disease (%) 25/32 (78) 113/279 (40.5) < 0.0001 9/14 (64.3) 0.09
Diabetes (%) 8/20 (40) 7/156 (4.4) < 0.0001 2/11 (18.2) 0.1
Coronaropathy (%) 2/16 (12.5) 4/279 (1.4) 0.03 2/11 (18.2) 0.018
Mean n. Framingham risk factors at the CV event (SD) 11.1 (10) 5.98 (7.2) 0.0001b 18.54 (14.5) < 0.0001b