Table 1: Summary of the
effects of GsCG and its components on the IL-1β stimulated C-20/A4 chondrocyte cell line.
GsCG |
Gs |
GR |
Cu |
|
NOX4 activity |
++ |
- |
++ |
++ |
ADAMTS5 pro-MMP1 |
++ |
++ |
- |
- |
++ |
- |
++ |
++ |
|
Viability Caspase 3 |
++ |
++ |
- |
- |
++ |
++ |
- |
++ |
|
HO-1 |
++ |
++ |
- |
++ |
++ Significant impact; +
Potential impact; – No impact