Table 1: AT-RvD1 and Dexamethasone treatment reduce apoptosis in submandibular glands from NOD/ShiltJ mice (raw data). NOD/ShiltJ mice were systemically injected via tail vein injections with the following treatments: (A) NaCl (0.9%), (B) AT-RvD1 (0.01-0.1 mg/kg) and (C) dexamethasone (DEX; 8.25 mg/Kg) 2 times a week for 14 weeks. At 18 weeks of age, submandibular glands were removed, frozen, and sections from were fixed and evaluated by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick-end labeling (TUNEL). The results are from 3 biological replicates.

Raw data for TUNEL analysis.

	Mean Intensity (Normalized values)
Treatments	n = 1		n = 2		n = 3
NaC10.9%	134.5468	(−2.083)	17.159	(−0.584)	1.2283	(−0.785)
RvD10.1 mg/kg	25.04571	(−0.492)	2.5511	(−0.299)	0.771	(−0.55)
DEX 8.25 mg/kg	7.404106	(−0.236)	3.5235	(−0.741)	5.4319	(−2.941)
Positive	25.40182		2.1055		36.426
Negative	6.902441		0.0217		0.0075

Positive and negative rows indicate TUNEL experimental controls with and without DNase I respectively as indicated in the manufacturer's instructions. Positive and negative controls were performed in frozen mouse sub man dibular gland sections from C57BL/6 mice.