Table 3: Effects of psychiatric disorders on weight loss outcome.
Author and Publication year |
Country |
Study features |
N Participants |
Mean age |
Sex |
Other features of
the study |
Surgery/setting |
Instruments |
Results |
White et al.
2015 [44] |
New Haven, USA |
Prospective, longitudinal study |
357 |
|
|
To examine the prognostic
significance of depressive symptoms in bariatric surgery patients over 6- 12-
24-months of follow up. |
RYGB |
Beck Depression Inventory |
Depressive symptoms characterized
45 % of patients prior to surgery, and 12 % at 6-month
follow-up, 13 % at 12-month follow-up, and 18 % at 24-month
follow-up. Preoperative depressive symptoms did not predict
postoperative weight outcomes. Postsurgery depressive symptoms were
predictive of weight loss outcomes. |
Steinmann WC et
al. 2011 [92] |
Columbia USA |
Retrospective study |
|
|
|
Comparison of patient underwent
to RYGB: bipolar disorder group, other psychiatric conditions group, without
psychiatric diagnosis group |
RYGB |
Evaluation of the differences
in demographics, physical comorbidities, and psychological conditions before
surgery and behavioural noncompliance after surgery. |
At 1 year, overall mean percent
weight loss exceeded 35%, and mean BMI was 32. These outcomes were remarkably
similar and not significantly different for those with bipolar disorder,
other psychological conditions, and those without. |
Legenbauer et al.
2011 [103] |
Bochum, Germany |
Prospective, longitudinal study |
153 |
38.8% |
66.9% F |
Lifetime diagnosis of a mental
disorder was defined as presence of a mental disorder only in the past. Body
weight was measured at baseline, 1 year after baseline, and 4 years after
baseline. |
Bariatric surgery |
Munich-CIDI to assess current
and lifetime depressive disorders including |
Depression was not associated
with weight changes at the 1-year follow-up. After 4 years: depression
(current and lifetime) predicted smaller body mass index loss, whereas
lifetime diagnosis of eating disorder was associated with greater weight
loss. |
Semanschin-Doerr DA et al. 2010 [50] |
Cleveland, USA |
Prospective, longitudinal study |
104 |
|
78.6% white, 71.2% F |
43.1% had a current, and 62.5%
a lifetime, diagnosis of a mood disorder. 1-Year follow-up |
Sleeve gastrectomy |
|
Patients with current or
lifetime mood disorders had a significantly lower %EWL. After removing
patients with bipolar disorder from the analyses, no significant differences
were found in the %EWL between patients with and without a lifetime history
of depressive disorders. |
Thonney et al.
2010 [56] |
Geneva, Switzerland |
Prospective, longitudinal study |
43 |
39.3 ± 1.4 |
F |
2 years follow up |
RYGB |
BDI; Hospital Anxiety and
Depression Scale |
Decreases in depression,
anxiety (P <.05), and eating disorder scores were measured 2 years after
surgery. Both excess weight loss and change in body mass index were
associated with improvements in all measured psychological outcomes 2 years
after surgery. |
Coleman et al.
2010 [55] |
Pasadena (USA) |
Prospective, longitudinal study |
110 |
43,5 |
F |
1-year follow up |
RYGB |
Evaluation of the differences
in demographics, physical comorbidities, and psychological conditions before
surgery and behavioural noncompliance after surgery. |
The only differences between
patients with successful and unsuccessful weight loss were found for sleep
apnea before surgery, exercise noncompliance in the second year after
surgery, and dumping syndrome in the first 6 months after surgery. |
Legenbauer et al.
2009 [49] |
Dortmund,Germany |
Prospective, longitudinal study |
531 (151 BS) |
38.8 ± 10.3 |
66.9 % F in BS group, white |
To investigate the impact of
current mental disorders on weight loss: 4-year follow-up |
Comparison participants in a conventional treatment,
obesity surgery patient, obese control individuals |
|
Patients with a depressive
and/or anxiety disorder lost significantly less weight compared with those
without a comorbid mental diagnosis. Binge eating behaviour at baseline did
not predict weight loss at 4-year followup. |
Kalarchian et al.
2008 [69] |
Pittsburgh, USA |
Prospective, longitudinal study |
207 (97.2% white) |
45.8 ± 9.5 |
83.1% F; 16.9% M |
6-month follow up |
RYGB |
SCID-I |
Lifetime mood disorder was
associated with a smaller decrease in BMI. |
Averbukh Y et al. 2003 [22] |
New York |
Prospective, longitudinal study |
145 |
|
|
to evaluate the association
between pre-surgical severity of depression and success at weight loss
following Roux-en-Y gastric bypass (RYGBP) |
RYGB |
BDI |
Weight loss at 1 year was
significantly related to the BDI score before surgery. BDI score was also
found to be a significant predictor of the amount of weight lost (kg) 1 year
after surgery. |
F: Female; M: Male; BS:
Bariatric Surgery; BMI: Body mass Index; RYGB: Roux-Y-Gastric Bypass; LAGB:
Laparoscopic Adjustable Gastric Banding; MDD: Major Depressive Disorder; BD:
Bipolar Disorder; BED: Binge Eating Disorder; SCID-I: Structured Clinical
Interview for DSM IV Axis I disorders; Ham-D: Hamilton Rating Scale for
Depression; BDI: Beck Depression Inventory; Beck Depression Inventory-II (BDI-II); QoL: Quality of Life