Table 3: Effect of inhibitors dexamethasone, actinomycin-D, cyclohexamide and retinoic acid on MMP-2 and MMP-9 secretion in laryngeal squamous cell carcinoma (FaDu) and tongue cancer cells (SCC-25).
| Larygneal squamous cell carcinoma (FaDu) | Tongue cancer cells (SCC-25) | |||
| MMP-2 (%) | MMP-9 (%) | MMP-2 (%) | MMP-9 (%) | |
| Dexamethasone (μM) | ||||
| Control | 40.2 | 49.8 | 30.6 | 26.3 |
| 50 | 0 | 10 | 27.9 | 15.2 |
| Actinomycin-D (μg/ml) | ||||
| Control | 19.8 | 53.8 | 23.2 | 19.9 |
| 2 | 0 | 26.4 | 18 | 11.4 |
| 4 | 0 | 0 | 16.8 | 10.8 |
| Cyclohexamide (μg/ml) | ||||
| Control | 22.9 | 22.4 | 44.9 | 36.6 |
| 2 | 22.7 | 12.8 | 4.5 | 1.7 |
| 4 | 15 | 4.2 | 3.6 | 6.6 |
| Retinoic Acid (μM) | ||||
| Control | 42.3 | 55.8 | 53.8 | 46.2 |
| 50 | 0 | 1.9 | 0 | 0 |