Table 3: Demographic and clinical characteristics of the patients according to scleroderma pattern. In bold and gray background, the comparisons that present statistical significance (p < 0.05) are highlighted.
|
Parameters |
Scleroderma pattern |
Non-scleroderma pattern |
p-value* |
p-value** |
p-value*** |
|||||
|
Total (n = 10) |
Early (n = 0) |
Active (n = 8) |
Late (n = 2) |
Total (n = 14) |
Normal (n = 9) |
Non specific abnormalities (n = 5) |
||||
|
Age (years) |
53.0 ± 14.7 |
N/A |
51.1 ± 13.7 |
60.5 ± 21.9 |
51.1 ± 16.7 |
49.1 ± 17.1 |
54.8 ± 17.1 |
0.7804 |
|
|
|
Raynaud’s phenomenon |
10 (100%) |
N/A |
8 100%) |
2 (100%) |
2 (14.3%) |
0 (0%) |
2 (40%) |
< 0.0001 |
1.0000 |
0.1099 |
|
Capillaroscopy characteristics |
||||||||||
|
Density (/mm) |
4.5 ± 1.4 |
N/A |
5.0 ± 0.9 |
2.5 ± 0.7 |
9.6 ± 2.5 |
10.7 ± 2.5 |
7.8 ± 1.1 |
< 0.0001 |
0.0079 |
0.0332 |
|
Dimension (µm) |
74.4 ± 31.8 |
N/A |
84.9 ± 25.6 |
32.5 ± 10.6 |
16.9 ± 4.5 |
14.7 ± 1.2 |
21.0 ± 5.5 |
0.0003 |
0.0066 |
0.0633 |
|
Abnormal morphology |
10 (100%) |
N/A |
8 (100%) |
2 (100%) |
1 (7.1%) |
0 (0%) |
1 (20%) |
< 0.0001 |
1.0000 |
0.3571 |
|
Haemorrhages |
8 (80%) |
N/A |
8 (100%) |
0 (0%) |
3 (21.4%) |
0 (0%) |
3 (60%) |
0.0111 |
0.0222 |
0.0274 |
|
Antibodies |
||||||||||
|
ANA |
9 (90%) |
N/A |
7 (87.5%) |
2 (100%) |
1 (7.1%) |
0 (0%) |
1 (20%) |
< 0.0001 |
1.0000 |
0.3571 |
|
SCL-70 |
1 (10%) |
N/A |
1 (12.5%) |
0 (0%) |
1 (7.1%) |
0 (0%) |
1 (20%) |
1.0000 |
1.0000 |
0.3571 |
|
ACA |
5 (50%) |
N/A |
4 (50%) |
1 (50%) |
0 (0%) |
0 (0%) |
0 (0%) |
0.0059 |
1.0000 |
1.0000 |
*P-value between patients with scleroderma pattern and Non-scleroderma pattern (Student’s t-test or Chi Square); **p-value between Active and Late (t-Student or Chi Square); ***p-value between normal and non-specific abnormalities (t-Student or Chi Square); N/A does not apply.