Table 2: Demographic, clinical, and laboratory characteristics of the patients and controls. In bold and gray background, the comparisons that present statistical significance (p < 0.05) are highlighted.
|
Parameters |
Control (n = 12) |
Systemic sclerosis |
p-value* |
p-value** |
||
|
All (n = 12) |
IcSS (n = 7) |
dcSS (n = 5) |
||||
|
Age (years) |
52.8 ± 16.5 |
51.0 ± 15.3 |
50.9 ± 16.2 |
51.2 ± 15.8 |
0.7802 |
0.9716 |
|
Time of disease (years) |
N/A |
12.7 ± 8.5 |
9.4 ± 7.3 |
17.4 ± 8.4 |
N/A |
0.1069 |
|
Raynaud’s phenomenon |
0 (0%) |
12 (100%) |
7 (100%) |
5 (100%) |
< 0.0001 |
1.0000 |
|
Capillaroscopy characteristics |
||||||
|
Density (/mm) |
10.1 ± 2.4 |
4.9 ± 1.6 |
4.4 ± 1.6 |
5.6 ± 1.5 |
< 0.0001 |
0.2337 |
|
Dimension (µm) |
16.4 ± 4.1 |
65.3 ± 35.7 |
70.7 ± 37.7 |
57.8 ± 35.5 |
0.0006 |
0.5627 |
|
Abnormal morphology |
0 (0%) |
11 (91.7%) |
7 (100%) |
4 (80%) |
< 0.0001 |
0.4167 |
|
Haemorrhages |
1 (8.3%) |
10 (83.3% |
5 (71.4%) |
5 (100%) |
0.0010 |
0.4697 |
|
Antibodies |
||||||
|
ANA |
0 (0%) |
10 (83.3%) |
7 (100%) |
3 (60%) |
0.0002 |
0.1515 |
|
SCL-70 |
0 (0%) |
2 (16.7%) |
0 (0%) |
2 (40%) |
0.4602 |
0.0454 |
|
ACA |
0 (0%) |
5 (41.7%) |
4 (57.1%) |
1 (20%) |
0.0373 |
0.2929 |
*P-value between control and all patients (t-Student or Chi Square); **p-value between IcSS and dcSS (t-Student or Chi Square); N/A does not apply.