Table 2: Severity scores, stay, clinical respond, and outcomes in Ceftaroline group versus another antibiotic.

 

Ceftaroline

(N = 34) (28.1%)

Another Antibiotic

(N = 87) (71.9%)

p

Severity of clinical presentation

 

 

 

SOFA at admission

7.6 ± 2.9

5.6 ± 3.01

0.001

FINE

4.4 ± 0.7

3.6 ± 1.2

0.001

Stay

 

 

 

Stay in ICU (days)

18.9 ± 15.5

9.4 ± 12.8

0.001

Stay in hospital (days)

28.9 ± 20.4

17.01 ± 19.1

0.003

Clinical response

 

 

 

Cure criteria: End of treatment

33 (97.1%)

66 (75.9%)

0.007

Clinical improvement in 72 hours

28 (82.4%)

47 (54%)

0.004

Mortality

 

 

 

Hospital death

6 (17.6%)

22 (25.3%)

0.370

Early death (< 3 days)

1 (25%)

8 (36.4%)

0.660

Death at 30 days

3 (75%)

12 (80%)

0.827

Related Mortality

0

12 (63.2%)

0.007

Another group includes treatment with ceftriaxone, piperacillin-tazobactam, cefepime or cloxacillin. Quantitative data are expressed like median ± standard deviation and categoric data like percentage; SOFA: Sequential Failure Assessment Score; ICU: Intensive care unit.