Table 1: Baseline characteristics of patients with COVID-19 in treatment (hydroxychloroquine and azithromycin combined) and control group (no hydroxychloroquine + azithromycin).

Variables Total (N = 208) Treatment group (N = 150) Control group (N = 58) p-value
  n (%) n (%) n (%)  
Patient age group        
< 45 years 67 (32.2) 46 (30.7) 21 (36.2) 0.739
45-64 years 94 (45.2) 69 (46.0) 25 (43.1)  
≥ 65 years 47 (22.6) 35 (23.3) 12 (20.7)  
Sex        
Female 84 (40.4) 63 (42.0) 21 (36.2) 0.445
Male 124 (59.6) 87 (58.0) 37 (63.8)  
Occupation        
Health professional 25 (12.0) 20 (13.3) 5 (8.6) 0.349
Others occupation 183 (88.0) 130 (86.7) 53 (91.4)  
Pre-existing medical condition        
Hypertension 54 (26.0) 45 (30.0) 9 (15.5) 0.033
Diabetes 27 (13.0) 23 (15.3) 4 (6.9) 0.104
Chronic lung disease 20 (9.6) 17 (11.3) 3 (5.2) 0.177
Others 51 (24.52) 37 (24.7) 14 (24.1) 0.937
Number of pre-existing conditions        
None 107 (51.4) 70 (46.7) 37 (63.8) 0.086
1 58 (27.9) 46 (30.7) 12 (20.7)  
≥ 2 43 (20.7) 34 (22.7) 9 (15.5)  
Number of days from symptoms onset to admission* 8 (6-12) 8 (6-13) 7 (4-10.5) 0.076
Clinical signs        
Cough 122 (58.6) 98 (65.3) 24 (41.4) 0.002
Fever 149 (71.6) 112 (74.7) 37 (63.8) 0.119
Dyspnoea 57 (27.4) 44 (29.3) 13 (22.4) 0.316
Asthenia 60 (28.9) 45 (30.0) 15 (25.9) 0.555
Clinical constants        
Temperature* 37.0 (36.5-37.5) 37.0 (36.5-37.5) 37.2 (36.7-38.0) 0.196
Systolic blood pressure* 131 (120-150) 136 (120-151) 130 (110-140) 0.113
Diastolic blood pressure* 82 (74.5-90) 82 (76-90) 80 (70-90) 0.653
Oxygen saturation* 95 (89-97) 95 (90-97) 95 (77-97) 0.279
Heart rate* 97 (84-110) 94 (83-105) 102 (88-112) 0.203

*Values presented are medians (inter-quartile ranges)