Table 2: Laboratory, Radiologic, and Severity Data on Admission for 48 Patients with Legionnaire’s Disease.

Variable

Value

no./no. tested subjects (%)

Leukocytosis (WBC ≥ 12 x 103/L)

32/48 (67)

Thrombocytopenia (Platelets ≤ 100 x 103/L)

4/48 (8)

New-Onset Renal failure (Cr > 2.0 mg/dl)

11/44 (25)

Hyponatremia (Na ≤ 130 mEq/l)

14/48 (29)

Aspartate Aminotransferase (AST) (≥ 40 UI)

34/48 (71)

Alanine Aminotransferase (ALT) (≥ 40 UI)

17/48 (35)

Rhabdomyolysis (CPK ≥ 1000 U/L)

12/39 (31)

Lipase > 480 U/L (3 x upper limit of normal)

11/29 (38)

Procalcitonin (> 0.5 ug/l)

15/17 (88)

Lactate (> 2.0 mmol/L)

8/27 (30)

Hematuria

32/42 (76)

Sputum Culture Positive

13/24 (54)

Urine Legionella Antigen Positive

45/47 (96)

Chest radiograph Findings

Unilateral infiltrate

Bilateral infiltrates

Normal

Unilobar infiltrates

Multilobar infiltrates

38/48 (71)

9/48 (12)

1/48 (2)

16/48 (33)

31/48 (65)

Pittsburgh Pneumonia Severity Index

1

2

3

4

5

5/48 (10)

13/48 (27)

13/48 (27)

10/48 (21)

7/48 (15)

Apache II Score (19 ICU patients) -------- Mean +/- SD

16.4 +/- 5.0