Table 3: Clostridium difficile colitis complications before and after protocol implementation.
| Parameters | Before "Per IDSA Guidelines" | Before "Off IDSA Guidelines" | After "Per Hospital Protocol" | After "Off Hospital Protocol" | p-value |
|---|---|---|---|---|---|
| All patients | n = 332 | n = 82 | n = 277 | n = 71 | |
| Total complications | 14.5% | 23.2% | 10.5% | 16.9% | 0.0288 |
| 4-week recurrence | 8.1% | 4.9% | 6.9% | 8.5% | 0.7389 |
| Mortality | 7.8% | 18.3% | 4.0% | 11.3% | 0.0002 |
| NAP1a strain positive | n = 92 | n = 27 | n = 72 | n = 15 | |
| Total complications | 20.7% | 37.0% | 13.9% | 20.0% | 0.0901 |
| 4-week recurrence | 14.1% | 3.7% | 9.7% | 6.7% | 0.4156 |
| Mortality | 9.8% | 33.3% | 4.2% | 13.3% | 0.0006 |
| NAP1 strain negative | n = 240 | n = 55 | n = 205 | n = 56 | |
| Total complications | 12.1% | 16.4% | 9.3% | 16.1% | 0.3416 |
| 4-week recurrence | 5.8% | 5.5% | 5.9% | 8.9% | 0.8323 |
| Mortality | 7.1% | 10.9% | 3.9% | 10.7% | 0.1294 |
aNAP1: North American Pulsed Field Type 1.