Table 1: The lancet concensus scoring system [2].
Diagnostic score | |
Clinical criteria | (maximum = 6) |
Symptoms of fever more than 5 days | 4 |
Systemic symptoms suggestive of tuberculosis: weight loss or night sweats, or persistent cough for more than 2 weeks | 2 |
Focal neurological deficit | 1 |
Cranial nerve palsy | 1 |
Altered consciousness | 1 |
CSF criteria | (maximum = 4) |
Clear appearance | 1 |
Cells (10-500 per microliter) | 1 |
Lymphocytic predominance (> 50%) | 1 |
Protein concentration (> 1 g/L) | 1 |
CSF to plasma glucose ratio of < 50% or an absolute CSF glucose concentration < 2.2 mmol/L | 1 |
Cerebral imaging criteria | (maximum = 6) |
Hydrocephalus | 1 |
Basal meningeal enhancement | 2 |
Tuberculoma | 2 |
Infarct | 1 |
Pre-contrast basal hyperdensity | 2 |
Evidence of tuberculosis elsewhere | (maximum = 4) |
Chest radiograph: signs if tuberculosis = 2; military tuberculosis = 4 | 2/4 |
CT/MRI/ultrasound evidence for tuberculosis (outside CNS) | 2 |
AFB identified or Mycobacterium tuberculosis cultured from another source - such as sputum, lymph node, gastric washing, urine, blood culture | 2 |
CT = Computed Tomogram, MRI = Magnetic Resonance Imaging, CNS = Central Nervous System, CSF = Cerebrospinal Fluid, AFB = Acid-Fast Bacilli.