Table 2:  Iron complexes with antimicrobial activity.

Compound *

Better activity than ligand against  (MIC)

Ref.

[Fe(L1)OAc](OAc)2a

S.aureus (n.p.), B. subtilis (n.p.), E.coli (n.p.), S. typhi (n.p.) and P. aeruginosa (n.p.)

[36]

[Fe(L1)Cl]Cl2, 

[Fe(L1)NO3](NO3)2a

E.coli (n.p.), S. typhi (n.p.) and P. aeruginosa (n.p.)

[FeL2(H2O)(OH)] ∙2H2Ob

S. aureus (2.7 µM), B. subtilis (2.7 µM), S. marcescens (2.7 µM), P. aeruginosa (2.3 µM) and E. coli (2.8 µM)

[37]

[FeL3(H2O)(OH)] ∙H2Ob

S. aureus (2.8 µM), B. subtilis (2.7 µM), S. marcescens (2.9 µM), P. aeruginosa (2.4 µM) and E. coli (2.9 µM)

[FeL4(H2O)(OH)] ∙H2Ob

S. aureus (3.3 µM), B. subtilis (3.2 µM), S. marcescens (3.3 µM), P. aeruginosa (2.9 µM) and E. coli (3.5 µM)

[FeL5(H2O)(OH)] ∙H2Ob

S. aureus (3.1 µM), B. subtilis (3.1 µM), S. marcescens (3.2 µM), P. aeruginosa (2.4 µM) and E. coli (2.9 µM)

[Fe(L6-H)3]c

M. tuberculosis (0.78  µg mL-1)

[38]

[Fe(L7-H)3]·5H2Oc

M. tuberculosis (3.9 µg mL-1)

[Fe(L8-H)3]·H2Oc

M. tuberculosis (0.78 µg mL-1)

[Fe(L9)2] 3+ d

S. aureus (0.202 mM), S epidermidis (0.101 mM), K. rhizophila (0.101 mM), B. subtilis (0.202 mM), P. aeruginosa (0.202 mM) and S. abony  (0.202 mM)

[39]

[Fe(Cl)2(L10)2] ]·2H2Oe

S. aureus (8.74 µg mL-1) and B. subtilis (10.33 µg mL-1)

[40]

 

aL1: C34H24N8O6:  Schiff base ligand that was synthesized by reacting 1,4-dicarbonyl-phenyl-dihydrazide and chromene-2,3- dione (2:2) poner nombre

bL2: 3- phenyl-4-amino-5-hydrazino-1,2,4-triazole; L3: 3-(2-chlorophenyl)-4-amino-5-hydrazino-1,2,4-triazole; L4:3-(4-chlorophenyl)-4-amino-5-hydrazino-1,2,4-triazole; L5: 3-(4-nitrophenyl)-4-amino-5-hydrazino-1,2,4-triazole

cL6: 3-aminoquinoxaline-2- carbonitrile N1, N4-dioxide; L7 = 3-amino-6(7)-methylquinoxaline-2-carbonitrile N1, N4-dioxide; L8 = 3-amino-6(7)-chloro-7(6)-methoxyquinoxaline-2-carbonitrile N1,N4-dioxide

dL9: Ethyl (2E)-2-[2-(diphenyl-phosphino)benzylidene]hydrazinecarboxylate

eL10: Chlorido-trans-[[2,20 -][(1,2-cyclohexanediyl) bis(nitrilomethylidyne)] bis[4-((2-methylimidazolium)methylene)-6-(t-Buphenolato)]

*All the chemical names were in accordance to bibliographic references

n.p: MIC not published