Table 2: Differences before and after treatment between SPIRO and AMLO groups.

Variable

SPIRO diff. (CI 95%)

AMLO diff. (CI 95%)

Effect

P-value

FPG (mg/dL)

0.8 (-2.53:4.13)

5.5 (1.37:9.57)

-4.7 (-10.25:0.90)

0.096

HOMA - IR

0.2 (-0.60:0.92)

0.8 (-0.17:1.75)

-0.6 (-1.86:0.61)

0.306

Potassium (mEq/L)

0.1 (-0.03:0.33)

0.1 (-0.08:0.35)

0.0

0.907

HDL-cholesterol (mg/dL)

4.6 (1.88:7.32)

1.8 (-1.44:5.15)

2.7 (-1.6:7.07)

0.202

Triglycerides (mg/dL)

-14.1 (-35.90:7.67)

-22.7 (-48.36:4.33)

7.9 (-26.52: 42.33)

0.639

hs-CRP (mg/L)

-1.0 (-1.93:-0.69)

1.9 (0.81:3.06)

-2.9 (-4.42:-1.45)

0.000

Plasma aldosterone (ng/dL)

9.15 (5.7:12.5)

0.83 (-3.75:5.41)

8.3 (2.53:14.11)

0.007

Urinary albumin excretion (mg/g creatinine)

-10.9 (-19.79:-1.99)

-0.19 (-11.62:11.23)

-10.7 (-25.63:4.24)

0.152

FMD (%)

4.9 (2.18:7.70)

-3.9 (-7.25:-0.54)

8.8 (4.39:13.28)

0.000

 

hs-CRP: C Reactive Protein-high sensitivity; Diff: Difference after-before treatment; Effect: Differences between differences in each group; FMD: Flow Mediated Dilation; FPG: Fasting Plasma Glucose; HDL: High Density Lipoprotein; HOMA IR: Homeostasis Model Assessment of Insulin Resistance.