Univariable

Multivariable

beta

95% CI

p

beta

95% CI

p

Age

-0.008

-0.009, -0.006

< 0.0001

-0.005

-0.008, -0.003

< 0.0001

Male

0.056

0.012, 0.099

0.0115

-0.006

-0.064, 0.051

0.8289

Poor ADL

-0.121

-0.169, -0.074

< 0.0001

-0.082

-0.136, -0.028

0.0029

Weight

0.005

0.003, 0.006

< 0.0001

-0.001

-0.003, 0.001

0.4383

Systolic BP, mmHg

0.001

-0.0002, 0.003

0.1037

Hemoglobin

0.019

0.009, 0.030

0.0004

0.001

-0.012, 0.014

0.8698

eGFR

0.001

0.0003, 0.002

0.0101

0.0002

-0.001, 0.001

0.6837

Gait speed

-0.041

-0.129, 0.047

0.3616

-0.354

-0.452, -0.255

< 0.0001

Hand grip strength

0.008

0.005, 0.010

< 0.0001

0.016

0.008, 0.025

< 0.0001

CONUT score

-0.012

-0.021, -0.003

0.0086

-0.013

-0.024, -0.001

0.0309

LN NT-proBNP

-0.018

-0.035, -0.001

0.0373

0.002

-0.017, 0.022

0.8117

LVMI

0.0002

-0.0002, 0.001

0.3830

LVEF

-0.001

-0.002, 0.001

0.3852

E/e

-0.0002

-0.003, 0.003

0.8725

e

0.005

-0.005, 0.016

0.3254

TAPSE

0.008

0.003, 0.012

0.0024

0.006

0.002, 0.011

0.0086

Change

d Hand grip strength

0.017

0.009, 0.025

< 0.0001

0.016

0.008, 0.025

< 0.0001

d CONUT score

-0.013

-0.024, -0.003

0.0119

-0.018

-0.030, -0.006

0.0035

d LN NT-proBNP

0.039

-0.067, -0.011

0.0065

-0.012

-0.042, 0.018

0.4196

d Weight

0.002

-0.002, 0.007

0.2489