Table 1: Clinical features upon initial presentation.

 

1

2

3

4

5

Age/Sex

72F

81F

77F

68F

72F

Diagnosis

SSc (diffuse)

SSc (diffuse)

SSc (diffuse)

SSc (diffuse)

SSc (diffuse)

Presenting complaint

Shortness of breath

Pseudo-obstruction

Shortness of breath

Pseudo-obstruction

Toe ulceration

Raynaud’s (duration)

-

+ (1 years)

+ (20 years)

+ (unknown)

+ (3 years)

Esophageal involvment

+

+

+

+

-

Proximal Skin involvement

+

+

+

+

+

Scleroderma facies

+

+

+

+

+

Telangiectasias

-

-

+

-

-

Synovitis

-

-

-

-

-

ANA

1:640

1:640

1:640

1:10,240

Not collected

Anti-centromere B

-

-

+ (87)

-

+ (155)

Anti-Scl-70

-

-

-

-

Not collected

Comorbidities

CAD

Pituiatary adenoma

CAD

Renel cell carcinoma

PAD

 

DM type II

Hypothyroidism

HTN

DM type II

DM type II

 

Osteopenia

HTN

Cervical spinal fusion

CHF

HTN

 

BPPV

Osteopenia

 

Asthama

 

 

ANA: antinuclear antibody; CAD: coronary artery diseases; DM: diabetes mellitus; BPPV: benign paroxysmal positional vertigo; HTN: hypertension; CHF: congestive heart failure.