Table 4: Association of SORL1 three-marker haplotypes (rs11218304-rs689021-rs11218343) with Amci

Haplotypes aMCI (freq) Controls (freq) Fisher's Punadj value OR (95% CI)
A-C-C 24.43 (0.194) 35.49 (0.099) 0.005062 2.206 (1.257-3.873)
A-C-T 24.51 (0.195) 66.69 (0.186) 0.819670 1.062 (0.633-1.780)
A-T-C 17.41 (0.138) 39.35 (0.110) 0.381657 1.308 (0.713-2.396)
A-T-T 44.65 (0.354) 169.47 (0.473) 0.021905 0.611 (0.400-0.933)
G-C-T 5.91 (0.047) 35.65 (0.100) 0.071315 0.447 (0.182-1.095)
G-T-T 5.93 (0.047) 4.18 (0.012) 0.016384 4.210 (1.183-14.978)

Freq = frequency. Haplotypes were omitted from analysis if the estimated haplotype probabilities were less than 3%