Table 1: Sample demographic and clinical
characteristics (n= 37,972).
|
Characteristics |
Controls (n = 23,447) N (%) |
Invasive Cases (n = 14,525) N (%) |
p-value2 |
|
Age (years) Mean ± SD |
55.6 ± 11.9 |
58.1 ± 11.3 |
<. 0001 |
|
< 40 |
2027 (8.7) |
748 (5.2) |
<. 0001 |
|
40-49 |
4771 (20.6) |
2544 (17.6) |
|
|
50-59 |
7403 (31.9) |
4537 (31.3) |
|
|
60-69 |
6098 (26.3) |
4324 (29.8) |
|
|
≥ 70 |
2892 (12.5) |
2343 (16.2) |
|
|
Family
history of ovarian cancer1 |
|
|
|
|
No |
15425
(92.0) |
8634 (82.4) |
<. 0001 |
|
Yes |
1351 ( 8.0) |
1849 (17.6) |
|
|
Age at
menarche (years) |
|
|
|
|
Mean ± SD |
12.9 ± 1.7 |
12.8 ± 1.6 |
0.0314 |
|
< 12 |
3128 (19.3) |
1856 (19.2) |
0.0772 |
|
12 |
3602 (22.2) |
2257 (23.4) |
|
|
13 |
4357 (26.9) |
2621 (27.1) |
|
|
≥ 14 |
5112 (31.6) |
2923 (30.3) |
|
|
Body mass inde × (kg/m2) |
|
|
|
|
< 25 |
3834 (48.2) |
2528 (45.1) |
0.0006 |
|
25-29 |
2332 (29.3) |
1681 (30.0) |
|
|
≥ 30 |
1797 (22.6) |
1396 (24.9) |
|
|
Oral
contraceptive use |
|
|
|
|
No |
6136 (37.5) |
4203 (43.7) |
<. 0001 |
|
Yes |
10230
(62.5) |
5419 (56.3) |
|
|
Histological
subtypes |
N/A |
|
|
|
Serous |
|
8369 (57.6) |
|
|
Endometroid |
|
2067 (14.2) |
|
|
Clear Cell |
|
1024 ( 7.1) |
|
|
Mucinous |
|
943 (
6.5) |
|
|
Others3 |
|
2122 (14.6) |
|
1for the first degree relatives
2t-test for a continuous variable and chi-square test for
a categorical variable
3Include mi × ed cell, other specified epithelial,
undifferentiated, unknown (but known to be epithelial), nonepithelial,
other or unknown if epithelial, or missing