Table 1: KDIGO, RIFLE, and AKIN AKI diagnostic criteria.
| Serum creatinine criteria | Urine output | |||
|---|---|---|---|---|
| AKI stage | KDIGO | RIFLE | AKIN | |
| 1 (R) | Increase ≥ 0.3 mg/dl within 48 h or ≥ 1.5- to 2-fold from baseline |
Increase × 1.5 baseline or GFR decrease > 25% | Increase 1.5-1.9 times from baseline or ≥ 0.3 mg/dl increase within 48 h |
< 0.5 ml/kg/h for 6-12 h |
| 2 (I) | 2.0-2.9 times from baseline | Increase × 2 from baseline or GFR decreased > 50% |
Increase > 2- to 3-fold from baseline | < 0.5 ml/kg/h for 12 h |
| 3 (F) | 3.0 times from baseline or increase in serum creatinine to ≥ 4.0 mg/dl or initiation of renal replacement therapy or, in patients < 18 years, decrease in eGFR to < 35 ml/min per 1.73 m2 |
Increase × 3 from baseline, or serum creatinine > 4 mg/dl) with an acute rise > 0.5 mg/dl or GFR decreased > 75% |
Increased > 300% (> 3-fold) from baseline, or ≥ 4.0 mg/dl with an acute increase of ≥ 0.5 mg/dl or on renal replacement therapy |
< 0.3 ml/kg/h for 24 h or anuria for 12 h |
R: Risk; I: Injury; F: Failure; KDIGO: Kidney Disease Improving Global Outcomes; RIFLE: The Risk, Injury, Failure, Loss, End-Stage; AKIN: Acute Kidney Injury Network.