Table 1: Patient characteristics, laboratory data and dialysis characteristics for each HD session.

 

 

H + HD

n (%)

H-HD

n (%)

P value

 

Patient number

67

298

 

Hemodialysis sessions

132

911

 

Age

59.8 15.2

60.1 13.8

0.87

Gender

Female

Male

 

72.3%

27.7%

 

47.2%

52.8%

 

< 0.001

Admission Diagnosis

Infection

Cardiovascular

Gastrointestinal

Surgery

Pulmonary

Neurologic

Renal

Endocrine

Hematologic

Other

 

41.7%

22.7%

8.9%

8.9%

5.9%

4.4%

3%

1.4%

1.4%

1.4%

 

38%

15.4%

9.3%

8.7%

6.4%

6.7%

5.0%

1.0%

5.7%

3.7%

 

Diabetes Mellitus

51.9%

57.6%

0.22

Systemic anticoagulation

Warfarin

IV heparin

Dalteparin

 

1.5%

0.8%

0

 

8.7%

2.9%

0.01%

< 0.001

DVT prophylaxis using heparin subcutaneous dosing

28.7%

40.1%

0.02

RBC transfusion

5.3%

5.6%

1.14

Hemoglobin (g/dl)

10.5 2.1

10.0 7.8

0.48

Platelet count (k/ul)

230 121.8

233 114.9

0.84

PTT (seconds)

30.3 12.0

34.6 16.9

< 0.001

INR

1.11 0.2

1.19 0.44

0.05

Type of HD vascular access

Arteriovenous fistula/Graft

Central venous catheter (both tunneled and untunneled)

 

44.3%

55.7%

 

42.1%

57.9%

 

0.88

Catheter heparin lock use

52.7%

48.3%

0.59

Heparin bolus dose administeredpre-HD

0

500 IU

1000 IU

2000 IU

 

0.8%

9.1%

89.4%

0.8%

 

 

Dialysis blood flow rate (ml/min)

330 45.1

335 44.7

0.53

Arterial chamber pressure (mmHg)

-179.7 43.7

-162.3 44.7

0.00

Venous chamber pressure (mmHg)

170.1 44.1

160.2 42.1

0.01

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

All data are presented as mean values SD. H + HD, heparin use dialysis session. H-HD: heparin free hemodialysis, PTT: Partial thromboplastin time, INR: International neutralization rate, DVT: Deep vein clot, RBC: Red blood cell, Catheter heparin lock dosing was 5000 unit/ml instilled post-HD.