Table 1: Comparison of studied variables between the three groups of ESRD patients, non-depression (GDS score ≤ 5), suggestive of depression (GDS score between 6 and 8) and depression (GDS score > 8).

 

Geriatric depression scale score less than or equal to 4

(n = 49)

Geriatric depression scale between 5 and 8

(n = 32)

Geriatric depression scale greater than or equal to 9

(n = 33)

P value

Sociodemographic data

Age, years

64.6 13.2

73.3 10.4 a)

65.1 15.8 b)

0.011

Gender, % male

67.3

40.6

36.4

0.090

Dialysis markers

URR, %

82.2 5.8

81.8 5.8

82.4 6.6

0.910

KTv

1.9 0.3

2.0 0.4

2.0 0.5

0.129

Creatinine, mg/dL

9.1 2.7

7.5 1.7 a)

7.1 2.3 a)

< 0.001

Substitution fluid volume, L

25.0 8.0

21.0 7.0

20.0 7.0 a)

0.009

Biochemical data

Potassium, mmol/L

5.1 0.6

4.9 0.6

4.8 0.8

0.154

Sodium, mmol/L

137.6 3.3

137.7 2.7

137.2 2.9

0.797

Phosphorus, mmol/L

4.3 0.8

4.2 1.4

4.0 0.8

0.529

Calcium, mg/dL

8.9 0.6

8.6 1.7

8.8 0.7

0.296

Calcium phosphorus product

38.2 8.4

36.7 11.9

35.4 9.1

0.437

Lipid profile

Total cholesterol, mg/dL

156.5 46.7

155.9 37.3

154.5 44.4

0.981

Triglycerides, mg/dL

157.7 82.5

119.6 76.1

129.3 59.6

0.062

HDLc, mg/dL

42.7 14.9

44.9 13.2

44.5 13.8

0.747

LDLc, mg/dL

82.2 39.5

86.9 32.9

84.2 38.4

0.855

Hematological data

Haemoglobin, g/dL

11.5 2.0

11.1 1.5

11.6 1.3

0.491

Haematocrit, %

34.7 6.5

33.9 4.8

35.4 4.4

0.562

Erythrocytes, x1012 /L

3.8 0.8

3.7 0.6

3.9 0.5

0.418

RDW, %

13.7 2.2

14.4 1.7

14.1 0.8

0.182

Platelets, x109/L

205.9 76.0

214.7 76.6

210.5 56.0

0.859

White blood cells, x109/L

6.3 1.8

6.9 2.9

6.8 2.4

0.379

Neutrophils, x109/L

3.9 1.4

4.5 2.0

4.7 2.2

0.184

Lymphocytes, x109/L

1.7 0.6

1.8 1.5

1.6 0.6

0.679

Neutrophil/Lymphocyte ratio

2.7 1.8

3.3 1.9

3.7 3.1

0.160

Iron status

Iron, mg/dL

71.8 31.2

65.2 24.7

63.5 33.7

0.431

Transferrin, mg/dL

179.1 30.6

167.3 26.7

173.4 27.8

0.200

Transferrin saturation, %

28.9 12.9

28.5 13.7

26.5 15.5

0.736

Ferritin, ng/mL

435.3 168.9

549.1 230.0

456.7 264.5

0.067

Nutritional markers

Total proteins, g/dL

6.9 0.4

6.9 0.4

6.7 0.6

0.114

Albumin, g/dL

3.8 0.6

3.6 0.7

3.5 0.7

0.351

BMI, Kg/m2

26.7 6.9

27.2 6.6

27.4 7.2

0.877

nPCR, g/kg/day

1.2 0.2

1.1 0.2

1.1 0.2

0.271

Relativefat, %

34.7 12.0

39.1 11.0

43.1 10.6 a)

0.006

FTI, kg/m2

13.5 5.9

15.4 5.8

17.1 6.8 a)

0.043

LTI, kg/m2

13.6 3.4

11.9 2.6

10.4 3.1 a)

< 0.001

LTM, kg

37.6 11.6

30.6 8.1 a)

27.4 10.8 a)

< 0.001

ATM, kg

36.5 15.2

39.1 14.0

42.3 13.5

0.214

OH, L

1.2 1.3

1.2 1.1

1.3 1.5

0.871

Abbreviated Lubben Social Network Scale

Abbreviated Lubben Social Network Scale, total score

17.7 7.1

16.3 6.9 a)

11.8 5.4 a) b)

0.001

 

a)    P < 0.05 vs. group I; b) P < 0.05 vs. group II.

CVC: Central venous catheter; URR: Urea reduction ratio; PTHi: Parathyroid hormone; RDW: Red cell distribution width; HDLc: High-density lipoprotein cholesterol; LDLc: Low-density lipoprotein cholesterol;

MCV: Mean cell volume; MCH: Mean cell haemoglobin; MCHC: Mean cell haemoglobin concentration; BMI: Body mass index; nPCR: Normalized protein catabolic rate; FTI: Fat tissue index; LTI: Lean tissue index;

LTM: Lean tissue mass; ATM: Adipose tissue mass; OH: Pre-dialysis hydration state