Table 1: Comparison of studied variables
between the three groups of ESRD patients, non-depression (GDS score ≤ 5),
suggestive of depression (GDS score between 6 and 8) and depression (GDS score
> 8).
|
|
Geriatric
depression scale score less than or equal to 4 (n
= 49) |
Geriatric
depression scale between 5 and 8 (n
= 32) |
Geriatric
depression scale greater than or equal to 9 (n
= 33) |
P
value |
|
Sociodemographic data |
||||
|
Age, years |
64.6 ± 13.2 |
73.3 ± 10.4 a) |
65.1 ± 15.8 b) |
0.011 |
|
Gender, % male |
67.3 |
40.6 |
36.4 |
0.090 |
|
Dialysis
markers |
||||
|
URR, % |
82.2 ± 5.8 |
81.8
± 5.8 |
82.4
± 6.6 |
0.910 |
|
KTv |
1.9
± 0.3 |
2.0
± 0.4 |
2.0
± 0.5 |
0.129 |
|
Creatinine, mg/dL |
9.1
± 2.7 |
7.5
± 1.7 a) |
7.1
± 2.3 a) |
< 0.001 |
|
Substitution fluid volume, L |
25.0 ± 8.0 |
21.0 ± 7.0 |
20.0 ± 7.0 a) |
0.009 |
|
Biochemical
data |
||||
|
Potassium, mmol/L |
5.1 ± 0.6 |
4.9 ± 0.6 |
4.8 ± 0.8 |
0.154 |
|
Sodium, mmol/L |
137.6 ± 3.3 |
137.7 ± 2.7 |
137.2 ± 2.9 |
0.797 |
|
Phosphorus, mmol/L |
4.3 ± 0.8 |
4.2 ± 1.4 |
4.0 ± 0.8 |
0.529 |
|
Calcium, mg/dL |
8.9 ± 0.6 |
8.6 ± 1.7 |
8.8 ± 0.7 |
0.296 |
|
Calcium phosphorus product |
38.2 ± 8.4 |
36.7 ± 11.9 |
35.4 ± 9.1 |
0.437 |
|
Lipid profile |
||||
|
Total cholesterol, mg/dL |
156.5 ± 46.7 |
155.9 ± 37.3 |
154.5 ± 44.4 |
0.981 |
|
Triglycerides, mg/dL |
157.7 ± 82.5 |
119.6 ± 76.1 |
129.3 ± 59.6 |
0.062 |
|
HDLc, mg/dL |
42.7 ± 14.9 |
44.9 ± 13.2 |
44.5 ± 13.8 |
0.747 |
|
LDLc, mg/dL |
82.2 ± 39.5 |
86.9 ± 32.9 |
84.2 ± 38.4 |
0.855 |
|
Hematological
data |
||||
|
Haemoglobin, g/dL |
11.5 ± 2.0 |
11.1 ± 1.5 |
11.6 ± 1.3 |
0.491 |
|
Haematocrit, % |
34.7 ± 6.5 |
33.9 ± 4.8 |
35.4 ± 4.4 |
0.562 |
|
Erythrocytes, x1012 /L |
3.8 ± 0.8 |
3.7 ± 0.6 |
3.9 ± 0.5 |
0.418 |
|
RDW, % |
13.7 ± 2.2 |
14.4 ± 1.7 |
14.1 ± 0.8 |
0.182 |
|
Platelets, x109/L |
205.9 ± 76.0 |
214.7 ± 76.6 |
210.5 ± 56.0 |
0.859 |
|
White blood cells, x109/L |
6.3
± 1.8 |
6.9
± 2.9 |
6.8
± 2.4 |
0.379 |
|
Neutrophils, x109/L |
3.9
± 1.4 |
4.5
± 2.0 |
4.7
± 2.2 |
0.184 |
|
Lymphocytes, x109/L |
1.7
± 0.6 |
1.8 ± 1.5 |
1.6
± 0.6 |
0.679 |
|
Neutrophil/Lymphocyte ratio |
2.7
± 1.8 |
3.3 ± 1.9 |
3.7
± 3.1 |
0.160 |
|
Iron
status |
||||
|
Iron, mg/dL |
71.8
± 31.2 |
65.2 ± 24.7 |
63.5 ± 33.7 |
0.431 |
|
Transferrin, mg/dL |
179.1
± 30.6 |
167.3
± 26.7 |
173.4
± 27.8 |
0.200 |
|
Transferrin saturation, % |
28.9
± 12.9 |
28.5
± 13.7 |
26.5
± 15.5 |
0.736 |
|
Ferritin, ng/mL |
435.3
± 168.9 |
549.1
± 230.0 |
456.7
± 264.5 |
0.067 |
|
Nutritional markers |
||||
|
Total proteins, g/dL |
6.9 ± 0.4 |
6.9 ± 0.4 |
6.7 ± 0.6 |
0.114 |
|
Albumin, g/dL |
3.8 ± 0.6 |
3.6 ± 0.7 |
3.5 ± 0.7 |
0.351 |
|
BMI, Kg/m2 |
26.7 ± 6.9 |
27.2 ± 6.6 |
27.4 ± 7.2 |
0.877 |
|
nPCR,
g/kg/day |
1.2 ± 0.2 |
1.1 ± 0.2 |
1.1 ± 0.2 |
0.271 |
|
Relativefat, % |
34.7 ± 12.0 |
39.1 ± 11.0 |
43.1 ± 10.6 a) |
0.006 |
|
FTI, kg/m2 |
13.5 ± 5.9 |
15.4 ± 5.8 |
17.1 ± 6.8 a) |
0.043 |
|
LTI, kg/m2 |
13.6 ± 3.4 |
11.9 ± 2.6 |
10.4 ± 3.1 a) |
< 0.001 |
|
LTM, kg |
37.6 ± 11.6 |
30.6 ± 8.1 a) |
27.4 ± 10.8 a) |
< 0.001 |
|
ATM, kg |
36.5 ± 15.2 |
39.1 ± 14.0 |
42.3 ± 13.5 |
0.214 |
|
OH, L |
1.2 ± 1.3 |
1.2 ± 1.1 |
1.3 ± 1.5 |
0.871 |
|
Abbreviated
Lubben Social Network Scale |
||||
|
Abbreviated Lubben
Social Network Scale, total score |
17.7
± 7.1 |
16.3 ± 6.9 a) |
11.8
± 5.4 a) b) |
0.001 |
a) P < 0.05 vs. group I; b) P < 0.05 vs. group II.
CVC: Central venous catheter; URR: Urea reduction
ratio; PTHi: Parathyroid hormone; RDW: Red cell
distribution width; HDLc: High-density lipoprotein
cholesterol; LDLc: Low-density lipoprotein cholesterol;
MCV: Mean cell volume; MCH: Mean cell haemoglobin; MCHC: Mean cell haemoglobin
concentration; BMI: Body mass index; nPCR: Normalized
protein catabolic rate; FTI: Fat tissue index; LTI: Lean tissue index;
LTM: Lean tissue mass; ATM: Adipose tissue mass; OH: Pre-dialysis
hydration state