Table 1: Summary of symptom concept expression
frequencies.
|
Symptom concepts, grouped by
sub-domain |
Number (%) of concept expressions
in transcripts (N = 521) |
Number (%) of transcriptsa
containing concept (N = 21) |
|
Energy-related symptoms |
110 (21) |
|
|
General tiredness |
68 (13) |
15 (71) |
|
Physical fatigue or tiredness |
30 (6) |
13 (62) |
|
Weakness |
9 (2) |
4 (19) |
|
Mental fatigue or tiredness |
3 (1) |
2 (10) |
|
Digestive symptoms |
92 (18) |
|
|
Decreased appetite |
18 (3) |
6 (29) |
|
Constipation |
16 (3) |
6 (29) |
|
Vomiting |
11 (2) |
4 (19) |
|
Restricted ability to urinate |
10 (2) |
4 (19) |
|
Bloating and fluid retention |
9 (2) |
4 (19) |
|
Nausea |
9 (2) |
5 (24) |
|
Diarrhea |
7 (1) |
6 (29) |
|
Change in urine |
4 (1) |
2 (10) |
|
Other digestive symptoms |
4 (1) |
3 (14) |
|
Weight change |
4 (1) |
2 (10) |
|
Dryness-related symptoms |
78 (15) |
|
|
Thirst |
41 (8) |
13 (62) |
|
Dry skin |
22 (4) |
9 (43) |
|
Dry mouth |
8 (2) |
6 (29) |
|
Itching |
7 (1) |
4 (19) |
|
Other dryness-related symptoms |
0 |
0 |
|
Pain and discomfort |
76 (15) |
|
|
Muscle cramping |
38 (7) |
14 (67) |
|
Headache |
15 (3) |
8 (38) |
|
General pain and discomfort |
9 (2) |
5 (24) |
|
Muscle soreness |
7 (1) |
5 (24) |
|
Bone and joint pain |
4 (1) |
2 (10) |
|
Chest pain |
3 (1) |
3 (14) |
|
Cognitive symptoms |
46 (9) |
|
|
Dizziness |
15 (3) |
8 (38) |
|
Light-headedness |
13 (2) |
7 (33) |
|
Impaired concentration |
11 (2) |
6 (29) |
|
Impaired memory |
7 (1) |
4 (19) |
|
Neuropathic symptoms |
42 (8) |
|
|
Swelling |
23 (4) |
9 (43) |
|
Tingling |
10 (2) |
5 (24) |
|
Restless legs |
5 (1) |
2 (10) |
|
Numbness |
4 (1) |
3 (14) |
|
Other neuropathic symptoms |
0 |
0 |
|
Sleep disruptions |
42 (8) |
|
|
Difficulty falling asleep |
19 (4) |
10 (48) |
|
Impaired sleep quality |
15 (3) |
8 (38) |
|
Difficulty staying asleep |
8 (2) |
5 (24) |
|
Additional symptoms |
19 (4) |
|
|
Impaired vision |
10 (2) |
3 (14) |
|
Blood pressure change |
7 (1) |
5 (24) |
|
Fever |
2 (<
0.5) |
1 (5) |
|
Respiratory symptoms |
16 (3) |
|
|
Cough |
7 (1) |
4 (19) |
|
Difficulty breathing and shortness of breath |
7 (1) |
6 (29) |
|
Other respiratory-related symptoms |
2 (<
0.5) |
2 (10) |
Sub-domains (bold type) and component
symptom concepts are shown in order of descending frequency.
aOne transcript represents one patient (21
patients included in study).