Table 2: Summary of the 5 cases of patients with H1N1 Influenza A infection and
AKI on ECMO support
|
|
Case 1 |
Case 2 |
Case 3 |
Case 4 |
Case 5 |
|
Age (years) |
59 |
64 |
42 |
56 |
38 |
|
Sex |
Female |
Male |
Male |
Female |
Male |
|
Hypertension |
No |
Yes |
No |
Yes |
No |
|
Diabetes |
Yes |
Yes |
No |
No |
No |
|
Dyslipidemia |
No |
Yes |
No |
No |
No |
|
Coronary artery
disease |
No |
Yes |
No |
No |
No |
|
Heart failure |
No |
No |
No |
No |
Yes |
|
Immunocompromised |
No |
No |
Yes |
No |
No |
|
Weight (kg) |
90 |
124.6 |
92.1 |
87.9 |
78 |
|
Body mass index
(kg/m2) |
33.4 |
38.5 |
29.1 |
33.1 |
25.5 |
|
H1N1 PCR
confirmed |
Yes |
Yes |
Yes |
Yes |
Yes |
|
Days in Hospital |
25 |
34 |
55 |
25 |
42 |
|
Days in ICU |
25 |
34 |
55 |
25 |
25 |
|
Days on ECMO |
19 |
34 |
21 |
20 |
9 |
|
Days on CRRT |
20 |
15 |
14 |
9 |
9 |
|
Days on
Ventilator |
23 |
34 |
55 |
23 |
9 |
|
SOFA Score |
14 |
8 |
17 |
16 |
12 |
|
APACHI II Score |
37 |
33 |
29 |
38 |
29 |
|
Day of Hospital
admission |
1/29/2014 |
1/17/2014 |
1/15/2014 |
1/29/2014 |
2/1/2014 |
|
Type of ECMO |
VV |
VV |
VV |
VV |
VA |
|
Onset of AKI
after initiation of ECMO |
Before |
19 days after |
20 days after |
Before |
Before |
|
CPK (u/L) |
18 |
26 |
21 |
404 |
1775 |
|
Schistocytes on
blood smear |
No |
No |
No |
No |
No |
|
Discharge |
SNF |
Death |
Death |
Death |
SNF |
*ICU: Intensive Care Unit, ECMO: Extracorporeal Membrane Oxygenation, CRRT:
Continuous Renal Replacement Therapy, SOFA: Sequential Organ Failure
Assessment, APACHEII: Acute Physiology and Chronic Health Evaluation II, AKI: Acute Kidney Injury,
CPK: Creatine Phosphokinase