Table
2: FDA approved first
line oral therapy for H. pylori treatment.
|
Therapy |
Duration
(days) |
Eradication
Rates |
Comments |
|
PPI
twice a day, clarithromycin 500 mg twice a day, amoxicillin 1 g twice a day |
10-14 |
70-85% |
Not
allergic to penicillin and have not received a macrolide. |
|
PPI
twice a day, clarithromycin 500 mg twice a day, metronidazole 500 mg twice a
day |
10-14 |
70-85% |
Allergic
to penicillin and have not received a macrolide. |
|
Bismuth
subsalicylate 525 mg four times a day, metronidazole 250 mg four times a day,
tetracycline 500 mg four times a day, PPI twice a day for 2 weeks, or H2RA
for 4 weeks. |
10-14 |
75-90% |
Those
allergic to penicillin or failed triple therapy or prevalence of
macrolide-resistance is > 20%. |
PPI:
Proton Pump Inhibitor, Lansoprazole 30 mg twice a day,
Omeprazole 20 mg twice a day, H2RA: Histamine 2 receptor antagonist [34,37].