Table 2: Ongoing clinical trials in Locally Advanced Esophageal Adenocarcinoma.

Agent(s)	Trial Design	Phase	ClinicalTrials.gov Identifier
Erlotinib	Concurrent chemoradiotherapy with Cis + Paclitaxel +/- Erlotinib in patients with locally advanced esophageal carcinoma	III	NCT00686114
Panitumumab	Concurrent chemoradiotherapy with FOLFOX + XRT + Panitumumab in patients with locally advanced adenocarcinoma of esophagus or GEJ followed by surgery	II	NCT01307956
Bevacizumab	Neoadjuvant and adjuvant FOLFOX with or without bevacizumab in treatment of locally advanced esophageal or GEJ tumors	II	NCT01212822
Trastuzumab	Concurrent chemoradiotherapy with carboplatin + paclitaxel + XRT with or without trastuzumab in patients with locally advanced esophageal or GEJ adenocarcinoma with HER2 overexpression	III	NCT01196390 (RTOG 1010)

(Cis: Cisplatin; XRT: Radiotherapy; GEJ: Gastroesophageal Junction)