Table 4: Multi-variate logistic regression of treatment failure among patients attending ART clinic at MKRH, 2021 (n = 133).
Variables |
Category |
n (%) |
COR (95%CI) |
AOR (95% C.I) |
p-value |
Age |
15-29 years |
42 (31.6) |
Ref |
Ref |
|
30-35 years |
43 (32.3) |
0.243 (0.195-2.830) |
0.675 (1.823-1.724) |
0.179 |
|
36-41 years |
30 (22.6) |
0.947 (0.690-3.864) |
1.021 (0.047-1.439) |
0.674 |
|
≥ 42 years |
18 (13.5) |
1.053 (0.867-9.142) |
2.04 (1.0761-5.902) |
0.002 |
|
Sex |
Male |
79 (59.4) |
Ref |
Ref |
|
Female |
54 (40.6) |
0.461 (0.289-2.157) |
0.926 (1.0281-1.034) |
0.496 |
|
Residency |
Urban |
85 (63.9) |
|
Ref |
|
Rural |
48 (36.1) |
2.819 (1.708-12.432) |
3.51 (1.951-11.430) |
0.001 |
|
Marital |
Single |
55 (41.4) |
Ref |
Ref |
|
status |
Married |
32 (24.1) |
0.971 (0.537-2.013) |
1.53 (0.183-1,8740) |
0.951 |
Divorced |
37 (27.8) |
1.016 (0.920-8.690) |
1.962 (0.427-2.942) |
0.008 |
|
Widowed |
9 (6.8) |
0.614 (0.152-4.916) |
0.385 (0.089-1.259) |
0.509 |
|
Living condition |
Alone in the house |
62 (46.6) |
Ref |
Ref |
|
Alone on the street |
9 (6.8) |
0.418 (0.317-3.197) |
0.75 (0.042-1.017) |
0.0543 |
|
With family/friends |
48 (36.1) |
0.752 (0.479-2.519) |
1.03 (0.073-1.079) |
0.193 |
|
Others |
14 (10.5) |
0.163 (0.019-3.185) |
0.431 (0.741-1.658) |
0.860 |
|
Initial ARV regimen |
D4T + 3TC + NVP (1a) |
36 (26.9) |
Ref |
Ref |
|
D4T + 3TC + EFV (1b) |
55 (41.0) |
0.815 (0.724-5.317) |
1.290 (0.1942-1.843) |
0.745 |
|
AZT + 3TC + NVP (1c) |
28 (20.9) |
1.932 (1.420-7.308) |
2.980 (1.1842-1.749) |
0.006 |
|
AZ + 3TC + EFV (1d) |
9 (6.7) |
0.393 (0.162-4.016) |
0.968 (0.047-1.123) |
0.906 |
|
Others |
6 (4.5) |
0.183 (0.021-3.901) |
0.371 (0.153-1.007) |
0.213 |
|
Duration of ARV treatment |
< 6 years |
47 (35.3) |
Ref |
Ref |
|
≥ 6 years |
86 (64.7) |
2.931 (2.042-13.510) |
3.15 (2.963-7.028) |
0.006 |
|
Diagnosis of recurrent pneumonia |
Yes |
60 (45.1) |
Ref |
Ref |
|
No |
73 (54.9) |
0.924 (0.631-9.012) |
1.47 (0.342-1.732) |
0.756 |
|
OI after initiate ART |
Yes |
48 (36.1) |
Ref |
Ref |
|
No |
85 (63.9) |
0.714 (0.417-6.710) |
0.915 (0.032-1.421) |
0.820 |
|
WHO stage of HIV |
Stage I |
24 (18.0) |
Ref |
Ref |
|
Stage II |
67 (50.4) |
0.917 (0.217-3.175) |
1.94 (1.132-1.4967) |
0.354 |
|
Stage III/IV |
42 (31.6) |
2.913 (1.824-7.308) |
3.97 (1.045-14.937) |
0.009 |