Table 1: Levels of iron parameters in various co-infected subgroups of HIV-1 positive donors at enrollment.

 

Subgroups of various co-infections in HIV-1 +ve donors

HPgV +ve

(n = 60)

TTV +ve

(n = 48)

HPgV -ve/TTV -ve

(n = 54)

Levels of iron parameters

Rep

(n = 38)

Vol

(n = 22)

Rep

(n = 16)

Vol

(n = 32)

Rep

(n = 19)

Vol

(n = 35)

HPgV viremia on follow up

Total

(n = 38)

Neg

(n = 24)

Pos

(n = 14)

Serum iron

 (µmol/L)

Mean

SD

31.9

10.6*

41.9

3.9**

26.1

8.7

14.9

4.4

31.3

4.9*

14.1

4.1

28.1

6.2*

13.1

2.6

Transferrin saturation (%)

Mean

SD

52.4

10.3*

62.8

5.6**

46.2

6.3

33.2

4.9

48.4

9.6*

34.3

4.2

53.6

7.5*

32.8

6.6

Serum ferritin

(µg/L)

Mean

SD

225

76.4*

299

41.5**

171

46.5

74

9.5

208

31.2*

72

8.8

211

33*

75

8.9

Statistical Comparisons: *P < 0.001 vs. Voluntary (Vol), **Significantly higher value vs. Pos (p < 0.001).

Note: The mean ± SD levels in non-donor controls (n = 50) for serum iron (µmol/L), transferrin saturation (%) and serum ferritin (µg/L) were 16.6 ± 3.2, 31.4 ± 4.6 and 80 ± 26.8 respectively.