Assessment of biochemical, immunological and virological parameters in HIV-1 positive donors at enrollment (values expressed as mean ± SD).

Table 2: Assessment of biochemical, immunological and virological parameters in HIV-1 positive donors at enrollment (values expressed as mean ± SD).

Laboratory parameters		Category of donors		Controls (n = 100)
Laboratory parameters		Replacement (n = 74)	Voluntary (n = 70)	Controls (n = 100)
Serum iron (µmol L^-1)		34.4 ± 9.2^*	18.2 ± 6.2	21.2 ± 4.9
TS (%)		48.8 ± 11.4^*	32.6 ± 7.2	34 ± 8.1
Serum ferritin (µg L^-1)		310 ± 42.4^*	98 ± 26.2	90 ± 24.8
Serum albumin (gm L^-1)		4.21 ± 0.36	4.32 ± 0.28	4.4 ± 0. 22
CD4 + T cell count	Enrollment	784 ± 96	812 ± 66	802 ± 86
CD4 + T cell count	Rate of fall/mth^#	12 ± 3.2^**	6 ± 2.1	ND
Viral load (log₁₀)	Enrollment	4.2 ± 0.22	3.9 ± 0.18	ND
Viral load (log₁₀)	Rate of increase/year^#	0.14 ± 0.06^**	0.08 ± 0.04	ND

*Significant elevation compared to controls; **Significant increase compared to voluntary donors; ND = Not done

# Calculated on the basis of values at enrollment and at 1 year of follow up.

Note: Elevated levels of iron parameters in replacement donors at enrollment came down within normal limits at the time of second TST in two step TST.