Table 1: End of AIDS, Epidemiologic control, HIV control, HIV elimination, HIV eradication and HIV extinction*.
| Category | Definition | Examples |
| End of AIDS (political) | Abstract political target of ending HIV as a major public health problem | Commonly used in political and public health discourse |
| End of AIDS (epidemiological) | Reduction of HIV incidence and AIDS to below one AIDS case per 1000 population [23]. The 90-90-90 and 95-95-95 targets are milestones on the way to the end of AIDS as they translate into 73% and 86% of people being virally suppressed, respectively [37]. The Global Plan calls for the elimination of maternal to child transmission to less than 5% transmission [35] | Leadership in New York State [44], Cambodia [45], San Francisco [46], Vancouver [47] are focused on HIV control, ending AIDS and getting to zero new infections |
| Epidemiologic Control | The point at which new HIV infections have decreased and fall below the number of AIDS-related deaths | PEPFAR 3.0 |
| HIV control | The reduction of HIV disease incidence, prevalence, morbidity, or morality to a locally acceptable level as the result of deliberate public health efforts; continued interventions will be needed to maintain the reduction and move towards elimination targets | San Francisco, Vancouver, |
| HIV elimination | Reduction of HIV and AIDS in a defined geographical area to below one AIDS case per 10,000 population per year and a reduction of HIV incidence to 1 new case per 10,000 population [23]. HIV-associated TB 1-5 per 1000 PLHIV per year. Deaths 5 per 1000 people living with HIV per year. Continued intervention measures including treatment are required to maintain elimination. | Cambodia |
| HIV eradication | Permanent reduction to zero of the worldwide incidence of HIV because of deliberate efforts. Intervention measures are no longer needed | None |
| HIV extinction | The specific agent no longer exists in the laboratory or nature; interventions are no longer needed | None |
*Table adapted from the Bulletin of the World Health Organization (1988) The principles of disease elimination and eradication [41].