Table 1: Demographic profile of patients and results of laboratory testing.
|
|
N = 15 |
|
Age (y) |
15.2 ± 3.5 |
|
Sex (male/female) |
8/7 |
|
Post transplant duration (mo) |
25 ± 23 |
|
Primary disease |
|
|
Urologic |
6 |
|
Chronic glomerulonephritis |
6 |
|
Tubulointerstitial nephritis |
1 |
|
Nephronophythisis |
1 |
|
Unknown |
1 |
|
Cyclosporine dosage (mg/kg/d) |
4.8 ± 1.4 |
|
Renal function (n) |
|
|
Stable patients |
10 |
|
Patients with CAD |
5 |
|
C0 (ng/mL) |
91.5 ± 62.1 |
|
C2 (ng/mL) |
561 ± 241 |
|
AUC (ng.h/mL) |
3380 ± 996 |
CAD: Chronic Allograft Dysfunction; C0: Serum Cyclosporine Trough Level; C2: serum Cyclosporine Second-Hour Level; AUC: Area under the Curve