Table 1: Patient demographics.
|
Pre-LAS SLT |
Pre-LAS BLT |
Post-LAS SLT |
Post-LAS BLT |
p-value |
|
|
(n = 64) |
(n = 6) |
(n = 37) |
(n = 34) |
||
|
Age (y) |
58.1 ± 5.5 |
56.5 ± 4.1 |
60.7 ± 4.6 |
57.9 ± 3.9 |
0.03 |
|
Gender (female) |
22 (34%) |
0 |
14 (38%) |
12 (35%) |
0.13 |
|
Race (Caucasian) |
62 (97%) |
4 (67%) |
36 (97%) |
30 (88%) |
< 0.001 |
|
BMI (kg/m2) |
24.4 ± 4.3 |
25.2 ± 4.2 |
23.6 ± 3.6 |
24.5 ± 3.6 |
0.73 |
|
FVC (% of predicted) |
52.3 ± 17.4 |
50.0 ± 11.4 |
46.8 ± 14.0 |
44.4 ± 15.3 |
0.08 |
|
FEV1 (% of predicted) |
20.1 ± 6.0 |
16.7 ± 3.7 |
18.1 ± 4.7 |
17.4 ± 4.0 |
0.04 |
|
Required oxygen (L) |
2.6 ± 1.3 |
3.8 ± 1.7 |
3.5 ± 3.1 |
3.0 ± 1.2 |
0.08 |
|
Assisted ventilation |
6 (9%) |
1 (16%) |
7 (19%) |
4 (12%) |
0.57 |
|
Systolic PAP (mmHg) |
34.8 ± 8.4 |
45.2 ± 8.0 |
38.9 ± 13.1 |
40.7 ± 11.1 |
0.02 |
|
Mean PAP (mmHg) |
25.4 ± 6.5 |
36.6 ± 6.5 |
27.0 ± 8.5 |
28.2 ± 8.8 |
0.006 |
|
PCWP (mmHg) |
14.2 ± 6.5 |
21.2 ± 9.6 |
13.1 ± 5.3 |
15.8 ± 7.4 |
0.03 |
|
Cardiac index (L/min/m2) |
2.9 ± 0.7 |
2.7 ± 1.0 |
2.9 ± 0.7 |
3.1 ± 0.7 |
0.6 |
|
Serum creatinine (mg/dl) |
0.9 ± 0.2 |
1.0 ± 0.2 |
0.9 ± 0.2 |
0.7 ± 0.2 |
0.001 |
|
History of diabetes |
5 (8%) |
2 (33%) |
12 (32%) |
9 (27%) |
0.006 |
|
Time on waiting list (d) |
367 ± 258 |
295 ± 223 |
475 ± 400 |
410 ± 550 |
0.5 |
|
LAS estimation |
32.8 ± 2.0 |
34.5 ± 1.4 |
36.0 ± 9.4 |
34.8 ± 2.3 |
0.03 |
|
Cardiopulmonary bypass |
4 (6%) |
3 (50%) |
5 (14%) |
33 (97%) |
< 0.001 |
|
Cold ischemic time (min) |
359 ± 145 |
492 ± 243 |
293 ± 101 |
229 ± 62 |
< 0.001 |
|
Donor age (y) |
32.0 ± 11.9 |
29.0 ± 15.2 |
29.1 ± 16.0 |
36.3 ± 17.0 |
0.33 |
|
Donor gender (female) |
20 (31%) |
0 |
11 (30%) |
11 (32%) |
0.15 |
|
Donor (Caucasian) |
16 (25%) |
2 (33%) |
26 (70%) |
18 (53%) |
< 0.001 |
LAS:
Lung Allocation Score; BMI: Body Mass Index; FVC: Forced Vital Capacity; FEV1:
Forced Expiratory Volume in 1 second; PAP: Pulmonary Arterial Pressure; PCWP:
Pulmonary Capillary Wedge Pressure.