Table
2: Chronic GVHD characteristics at enrollment (n = 19).
|
Platelet counts at onset, 109/L |
|
|
≥
100 (%) |
17 (89) |
|
<
100 (%) |
2 (11) |
|
Serum bilirubin (mg/dL) |
|
|
≥
2 (%) |
4 (21) |
|
<
2 (%) |
15 (79) |
|
Chronic GVHD type |
|
|
Classic
chronic GVHD (%) |
15 (79) |
|
Overlap
(%) |
4 (21) |
|
NIH severity |
|
|
Mild
(%) |
0 |
|
Moderate
(%) |
10 (53) |
|
Severe
(%) |
9 (47) |
|
Prior acute GVHD |
|
|
None
(%) |
6 (32) |
|
Grade
1 (%) |
5 (26) |
|
Grade
2 (%) |
7 (37) |
|
Grade
3 (%) |
1 (5) |
|
Grade
4 (%) |
0 |
|
Onset of cGVHD |
|
|
Progressive
(%) |
4 (21) |
|
De
novo (%) |
6 (32) |
|
Quiescent
(%) |
9 (47) |
|
Months from HSCT to cGVHD diagnosis |
|
|
Median
[Range] |
7 [3-16] |
|
Organs involved |
|
|
Mouth
(%) |
18 (95) |
|
Skin
(%) |
13 (68) |
|
Eye
(%) |
13 (68) |
|
Liver
(%) |
12 (63) |
|
Lung
(%) |
7 (37) |
|
Gastrointestinal
(%) |
4 (21) |
|
Joint
(%) |
2 (10) |
|
Genital
(%) |
1 (5) |
|
Multiple organs involvement |
|
|
3
(%) |
7 (37) |
|
4
(%) |
11 (58) |
|
5
(%) |
1 (5) |
|
Biopsy performed |
|
|
Yes
(%) |
14 (74) |
|
No
(%) |
5 (26) |