Absolute and relative organ weights in male Sprague-Dawley rats after repeated iv infusions of DINP and other test materials for 4 wk.

Table 2: Absolute and relative organ weights in male Sprague-Dawley rats after repeated iv infusions of DINP and other test materials for 4 wk.

Organ weight	Group
Organ weight	Control	125 mg/kg DINP	250 mg/kg DINP	500 mg/kg DINP	500 mg/kg DEHP
Absolute (mg)
Brain	1.9574 ± 0.0807	1.9756 ± 0.0856	1.9463 ± 0.0752	1.9373 ± 0.0655	1.8806 ± 0.0817
Heart	1.2031 ± 0.1450	1.1234 ± 0.1863	1.1420 ± 0.1119	1.2330 ± 0.1341	1.0915 ± 0.1334
Lung	1.8678 ± 0.1788	1.9829 ± 0.2449	1.9965 ± 0.2964	1.9031 ± 0.2561	2.2014 ± 0.6017
Liver	9.5856 ± 1.0196	9.1176 ± 1.3586	9.8095 ± 1.4348	10.1250 ± 1.6440	9.8836 ± 1.3135
Spleen	1.4766 ± 0.4775	1.1550 ± 0.4296^*	1.5232 ± 0.5913	1.3833 ± 0.3516	1.3007 ± 0.4053
Kidney	2.5899 ± 0.2692	2.4944 ± 0.2678	2.5748 ± 0.2805	2.6763 ± 0.2972	2.5544 ± 0.2175
Adrenal gland	0.0863 ± 0.0167	0.0978 ± 0.0208	0.0872 ± 0.0141	0.0968 ± 0.1855	0.0991 ± 0.0110
Testis	3.2537 ± 0.2344	3.2504 ± 0.2063	3.2313 ± 0.3194	3.2590 ± 0.2929	3.1878 ± 0.2325
Epididymis	1.1242 ± 0.1063	1.1465 ± 0.1270	1.0616 ± 0.0434	1.0794 ± 0.0595	1.0690 ± 0.1088
Prostate	0.5860 ± 0.1173	0.6233 ± 0.2110	0.5390 ± 0.1290	0.5735 ± 0.1141	0.5677 ± 0.1066
Relative (%)
Brain	0.0056 ± 0.0005	0.0059 ± 0.0005	0.0058 ± 0.0007	0.0055 ± 0.0003	0.0060 ± 0.0003
Heart	0.0034 ± 0.0003	0.0033 ± 0.0004	0.0034 ± 0.0004	0.0035 ± 0.0003	0.0035 ± 0.0004
Lung	0.0053 ± 0.0006	0.0059 ± 0.0009	0.0060 ± 0.0013	0.0054 ± 0.0006	0.0069 ± 0.0017^**
Liver	0.0275 ± 0.0019	0.0270 ± 0.0021	0.0295 ± 0.0048	0.0289 ± 0.0030	0.0314 ± 0.0028^**
Spleen	0.0042 ± 0.0013	0.0034 ± 0.0011	0.0045 ± 0.0016	0.0039 ± 0.0009	0.0041 ± 0.0010
Kidney	0.0074 ± 0.0006	0.0074 ± 0.0003	0.0077 ± 0.0008	0.0076 ± 0.0006	0.0081 ± 0.0006^*
Adrenal gland	0.0002 ± 0.0000	0.0003 ± 0.0001	0.0003 ± 0.0001	0.0003 ± 0.0001	0.0003 ± 0.0001
Testis	0.0093 ± 0.0009	0.0097 ± 0.0008	0.0098 ± 0.0016	0.0093 ± 0.0007	0.0102 ± 0.0008
Epididymis	0.0032 ± 0.0004	0.0034 ± 0.0003	0.0032 ± 0.0004	0.0031 ± 0.0003	0.0034 ± 0.0004
Prostate	0.0016 ± 0.0003	0.0018 ± 0.0005	0.0016 ± 0.0003	0.0016 ± 0.0002	0.0018 ± 0.0002

Data are mean ± SD (n = 9-10); *P < 0.05; ^**P < 0.01; Compared with the control group.