Table 1: Body weight changes after i.v. administration of different doses of DINP and other test materials in male Sprague-Dawley rats for 4 wk.
Treatment | Dose (mg/kg) | Time since treatment (wk) | |||
1 | 2 | 3 | 4 | ||
Control | - | 292.25 ± 14.97 | 329.49 ± 19.03 | 359.48 ± 27.75 | 348.49 ± 26.79 |
DINP | 125 | 291.64 ± 11.40 | 325.68 ± 15.12 | 359.65 ± 21.29 | 335.52 ± 32.22 |
250 | 290.61 ± 15.27 | 325.91 ± 21.92 | 348.71 ± 47.08 | 334.96 ± 41.35 | |
500 | 302.48 ± 16.76 | 341.33 ± 19.95 | 361.07 ± 31.27 | 348.70 ± 27.65 | |
DEHP | 500 | 290.11 ± 9.04 | 323.09 ± 13.46 | 331.73 ± 22.10* | 313.13 ± 20.00** |
Data are mean ± SD (n = 9-10). *P < 0.05; **P < 0.01, compared with the control group.