Mechanism that may be involved in the onset and progression of sarcopenia

Table 2: Mechanism that may be involved in the onset and progression of sarcopenia.

Age-related (primary mechanism)	Sex hormones, apoptosis, mitochondrial dysfunction
Endocrine dysfunction	Corticosteroids, GH, IGF-1, abnormal thyroid function, insulin resistance
Neuro-degenerative diseases	Motor neuron loss
Inadequate nutrition/malabsorption	cachexia
Disuse	Immobility, physical inactivity zero gravity