Table 3: Comparison between levels of studied biomarkers
(IL-6, IL-8 and CRP) at different stages of the study according to survival of
patients$.
|
Biomarkers |
Stages |
Survival |
P value |
|
|
Survivor (n
= 25; 75.8%) |
Non-survivor
(n
= 8; 24.2%) |
|||
|
IL-6 (pg/ml) |
Admission |
8.2 (0.1-17) |
376.0 (26.3-511) |
z = 2.186
(0.03)* |
|
72 hours |
0.1 (0.1-7.2) |
1.6 (0.1-187.6) |
z = 0.855
(0.393) |
|
|
14th day
|
3.1 (0.1-23.2) |
76.3 (68.5-84.1) |
z =
2.05 (0.04)* |
|
|
IL-8 (pg/ml) |
Admission |
15 (9.9-28.9) |
29.2 (9.1-164.5) |
z =
0.661 (0.508) |
|
72 hours |
18.3 (11.2-53.5) |
13.9 (4.8-23.6) |
z =
0.95 (0.342) |
|
|
14th day
|
29.4 (12.8-155.8) |
97 (61.7-132.4) |
z =
0.501 (0.616) |
|
|
CRP (mg/L) |
Admission |
3 (1.8-3.4) |
2.4 (2.4-3.3) |
z =
0.498 (0.618) |
|
72 hours |
2.1 (0.4-2.7) |
1.8 (0.7-2.3) |
z =
0.15 (0.881) |
|
|
14th day
|
2.2 (0.6-3.5) |
3.1 (3-3.1) |
z =
0.602 (0.547) |
|
IL-6: interleukin 6,
IL-8: interleukin 8, CRP: C-reactive protein, z: Mann Whitney test, $
all data are presented in median and interquartile range (IQR), *significant at
p ≤ 0.05.