Table 1: Characteristics of the subjects

Subjects with CRS (n=49) Subjects without CRS (n=109)
Characteristics Never-smokers (n=22) Smokers (n=27) Never-smokers (n=69) Smokers (n=40)
Age, yr
(range)
55.8 ± 12.9
(40-82)
59.5 ± 11.2
(40-81)
57.5 ± 10.8
(40-80)
57.6 ± 13.3
(41-85)
Male gender, n (%) 8 (36.4) 23 (85.2) 15 (21.7) 32 (80.0)
Smoking index, packxyr 0 25.0 ± 26.6 0 30.9 ± 25.5
Severity of CRS on facial CT† 13.0 ± 4.4 11.5 ± 3.8 0.7 ± 0.8 1.0 ± 0.8
Nasal polyp, yes (%) 5 (22.7) 3 (11.1) 0 (0) 0 (0)
FVC, L 3.1 ± 0.9 3.3 ± 0.8 2.8 ± 0.6 3.6 ± 0.9
%FVC predicted, % 77.0 ± 7.2 91.4 ± 16.1 79.8 ± 6.1 98.0 ±13.8
FEV1, L 3.0 ± 2.8 2.3 ± 0.7 2.3 ± 0.6 2.7 ± 0.8
%FEV1 predicted, % 78.6 ± 7.3 75.0 ± 19.2 81.0 ± 6.3 85.3 ± 18.3
FEV1/FVC ratio 0.77 ± 0.07 0.69 ± 0.13 0.80 ± 0.06 0.74 ± 0.13
FEV1/FVC ratio <0.7, n (%)
GOLD stage I/II/III/IV‡
5 (22.7)
0/5/0/0
11 (40.7)
2/6/2/1
3 (4.3)
0/3/0/0
11 (27.5)
2/8/0/1
<LLN, n (%)
4 (18.2)
12 (44.4)
3 (4.3)
12 (30.0)
Blood eosinophil counts, /mm3 226 ± 21 268 ± 20 157 ± 10 152 ± 14
serum total IgE levels, IU/mL 114 ± 365 426 ± 586 117 ± 175 303 ± 783


†, The severity of CRS was based on the Lund-Mackay score on facial CT; ‡, spirometric GOLD classification. CRS: Chronic Rhinosinusitis, CT: Computed Tomography, FEV1: Forced Expiratory volume in 1 second, FVC: Forced Vital Capacity, GOLD: Global Initiative for Chronic Obstructive Lung Disease, Ig: Immunoglobulin, LLN: Lower Limit of the Normal