Table 1: Clinical features of children with diarrhoea related haemolytic uraemic syndrome divided into two cohorts, 1998-2008 and 2009-2020 and entire period.
|
Cohort A (1998-2008) |
Cohort B (2009-2020) |
Over whole period n/(%), Cohort A vs. B |
Number of children |
88 |
138 |
226 |
Mean age presentation (± SEM) |
3.75 ± 0.32 |
3.88 ± 0.26 |
NS |
E. coli 0157:H7 detected |
43 |
87 |
130 P = 0.011 |
Other bacteria identified Campylobacter jejuni Cryptosporidium Aeromonas species Viruses (Adenovirus) |
- 1 - - |
3 - 1 1 |
|
Mean prodrome duration (days) |
6.9 ± 0.4 |
5.9 ± 0.2 |
6.4 p = 0.04 |
Bloody diarrhoea |
58 |
110 |
168 (74.3) p 0.028 |
Seizures |
7 |
24 |
31 (13.7%) NS |
Jaundice |
13 |
21 |
34 (15) NS |
Acute hypertension |
31 |
40 |
71 (31.4) NS |
Anuria |
46 |
62 |
108 (47.7) NS |
Mean anuria duration (days) |
6.3 ± 0.6 |
5.9 ± 0.6 |
6.1 NS |
Number dialysed |
54 |
74 |
128 (56.6) NS |
Mean duration of dialysis |
9.4 ± 0.9 |
11.0 ± 0.77 |
10.2 NS |