Table 1: Laboratory findings and clinical information for four patients with IgD multiple myeloma: All IgD MM patients had high levels for SFLCs, and circulating plasma cells. Only the highest levels of free light chains are recorded in the table. All patients had multiple "monoclonal" bands, including patient 3 in whom IgD band overlapped transferrin band in beta region. The patient numbers are the same as in Figure 1.
|
Patient 1 |
Patient 2 |
Patient 3 |
Patient 4 |
Age |
70 |
68 |
75 |
69 |
Race |
African American |
White |
White |
White |
Sex |
Male |
Female |
Female |
Male |
Immunoglobulin type |
IgD Lambda |
IgD Lambda |
IgD Lambda |
IgD Kappa |
Conc. of Ig D band |
2.69 g |
0.84 g |
1.01 g (including transferrin) |
2.26 g |
IgD quantification mg/dL |
5260 |
1960 |
244 |
2442 |
IgA mg/dL |
38 |
26 |
67 |
16 |
IgG mg/dL |
358 |
371 |
672 |
278 |
IgM mg/dL |
20 |
20 |
65 |
15 |
Plasma cells in blood, %, range |
10 |
3 |
4 to 22 |
2 to 7 |
Highest Kappa FLC mg/L |
6.11 |
1.61 |
0.92 |
4110 |
Highest Lambda FLC mg/L |
2347 |
5214 |
5925 |
0.61 |
Lytic lesions |
None recorded |
Femur & humerus |
None recorded |
Multiple |
eGFR mL |
19 |
70 |
7 |
31 |
Hemoglobin g/dL |
7.9 |
6.8 |
8.8 |
8.7 |
Calcium mg/dL (Corrected for Alb) |
15.4 |
11 |
11.1 |
10.6 |
Other diagnoses |
Renal ca, Bladder rupture, HTN |
Psoriasis |
COPD, HTN, DM |
Alcohol use |
Survival in months |
1 |
14 |
43 |
31 |