Table 1: Experimental plan for control and test animals.

Groups

Experimental Plan

Remarks

Group 1

Were neither infected with Plasmodium berghei nor treated.

Negative control

Group 2

Were infected with Plasmodium berghei but not treated.

Positive control

Group 3

Were infected with Plasmodium berghei and treated with 10 mg/kg of chloroquine solution for 4 consecutive days.

Drug treatment control

Group 4

Were not infected but were administered with 800 mg/kg body weight of Vernonia amygdalina for 4 consecutive days.

Plant extract control

Group 5, 6, 7

Were infected with Plasmodium berghei and administered with Vernonia amygdalina plant extract at 400, 600, and 800 mg/kg body weight for 4 consecutive days.

Treatment