Table 1: The Current CAP protocol for prostate cancer grading and Gleason score standard.
Grade group | Gleason score | Definition |
1 | Less than or equal to 6 | Only individual discrete well-formed glands |
2 | 3 + 4 = 7 | Predominantly well-formed glands with lesser component of poorly formed/fused/cribriform glands |
3 | 4 + 3 = 7 | Predominantly poorly formed/fused/cribriform glands with lesser component (#) of well-formed glands |
4 | 4 + 4 = 8 | Only poorly formed/fused/cribriform glands |
3 + 5 = 8 | Predominantly well-formed glands and lesser component (##) lacking glands (or with necrosis) | |
5 + 3 = 8 | Predominantly lacking glands (or with necrosis) and lesser component (##) of well-formed glands | |
5 | 9 - 10 | Lack gland formation (or with necrosis) with or without poorly formed/fused/cribriform glands (#) |